兔抗nfkb2多克隆抗体技术规格 background: this gene encodes one of the subunits of the tranion factor complex nuclear factor-kappa-b (nfkb). the nfkb tranion factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune fu...
即nf kb 在接下来的十分钟我们要解决四个问题1什么是NFKB2他又有怎样的结构特征3在细胞中信号是如何进行传导的4对生命活动又有怎样的意义于1986年，Sen 等首次从鼠B淋巴细胞核提取物在信号通路子－KB（nuclear factor-kappa B,NF-KB)蛋白家族是一种多效性的转录因子，可以与多种基启动子部位的KB位点发生特异...
(NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 ...
et al. Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat. Med. 19, 358–363 (2013). CAS PubMed Google Scholar Kim, W. H. et al. Additive activation of hepatic NF-κB by ethanol ...
Gene SummaryThis gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can functio...
背景资料:This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex...
Tumor necrosis factor (TNF), a well-studied activator, initiates the process by binding to its receptor and recruiting TNF receptor death domain (TRADD). TRADD, in turn, binds to TNF receptor-associated factor 2 (TRAF-2), which then attracts NF-kB-inducible kinase (NIK). Both ...
中文名称:TRAF家族成员关联NFKB激活因子(TANK)重组蛋白英文名称:Recombinant TRAF Family Member Associated NFKB Activator (TANK) 保存条件:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月纯度规格:> 95% 产品类别:重组蛋白 TRAF家族成员关联NFKB激活因子(TANK)重组蛋白 ...
但纤溶酶原激活抑制物2(Plasminogen activator inhibitor type-2,PAI-2)启动子上有两个 21、KB位点。TNF-能刺激NF-KB促PAI-2的表达。Dechend也报道动脉粥样硬化时内皮细胞产生的PAI、组织因子等促凝血蛋白质的升高伴随着NF-KB的活化。而p65的持续活化则能促进uPA(urokinase-type PA)的表达,因为uPA启动子上也...
Adult male Liv-Ikk2ca mouse livers had induction of mRNAs of Ikk2 and classical NF-kB targets, as well as IKK1, NIK (activator of IKK1), and RelB, but no changes in markers of inflammation or fibrosis (by real-time PCR). Liv-Ikk2ca mice had reduction of prooxidative Cyp2e1 and...