英文名NF-kappaBeta activator 2 别名 3-[2-(2-fluoroanilino)-1,3-oxazol-5-yl]benzoic acid 产品名称 NF-kappa Beta 激活物2 分子结构 分子式 C16H11FN2O3 分子量 298.27 CAS 登录号 2375281-44-8 分子行输入简码SMILES C1=CC=C(C(=C1)NC2=NC=C(O2)C3=CC(=CC=C3)C(=O)O)F安全...
Receptor activator of nf-κb ligand (rankl) activates tak1 mitogen-activated protein kinase kinase kinase through a signaling complex containing rank, tab2, and traf6. Mol. Cell. Biol. 2002, 22, 992–1000. [Google Scholar] [CrossRef] [PubMed] Franzoso, G.; Carlson, L.; Xing, L.; ...
To assess the impact of MT on the rat articular cartilage matrix and cell metabolism, this study conducted immunological analyses targeting MMP-3, MMP-13, ADAMTS-4, Aggrecan, receptor activator of nuclear factor-κB ligand (RANKL), and COL2A1 within the cartilage. ICH (Figure 4) revealed tha...
[2]. Macrophages are crucial immunological regulators and mediators of inflammation; therefore, the secretion of macrophage-derived inflammatory cytokines, such as interleukin (IL)-1 and IL-6, is known to induce kidney damage and inflammation [3]. Inflammatory macrophages are activated and ...
LPS, an activator of inflammation, which can promote the secretion of pro-inflammatory cytokines, leading to a severe inflammatory response, is often used to induce inflammation in animal experiments [19]. Mon has been reported to possess anti-inflammatory effects as evidenced in various animal expe...
Particulate matter (PM) in the air can penetrate the respiratory system and cause various adverse health effects [1]. When PM enters the body, it triggers an inflammatory response and cytotoxicity in lung tissue [2]. Inhaling PM causes the release of cytokines and chemokines, which are signali...