It was suggested that Cyr61/NF-kB signaling pathway mediates the upregulation of IL-8 in response to cyclic stretch in A594 cells. These findings support the hypothesis that Cyr61 plays a critical role in acute lung inflammation triggered by mechanical strain.Yan ZHANG...
Our data indicate the possible involvement of the NF-κβ/Iκβ/IκKβ signaling pathway in LPS-induced inflammatory response, and that the anti-inflammatory effect of RPO may be exerted via this pathway. Figure 4. RPO inhibits NF-κβ activation in LPS-induced rats. RPO reduced hepatic ...
Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for...
text>Background: To investigate the regulation of SURVIVIN by E2F1 through the classical NF kappa B activation pathway and to elucidate the effects of E2F1 on the biological functions of esophageal cancer cells. Materials and methods: An E2F1-overexpression plasmid, pGV142-E2F1, was constructed and...
NF-kappa-B inhibitor beta (NFKBIB) is a member of the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thus all...
Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA ...
Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thus allowing activation of the NF-kappa-B, which translocates to the nucleus to act as a transcription factor. Description NFKBIB Human Recombinant produced in E.Coli is a ...
et al. Polyhydroxylated Metallofullerenols Stimulate IL-1 beta Secretion of Macrophage through TLRs/MyD88/NF- kappa B Pathway and NLRP3 Inflammasome Activation. Small 10, 2362-2372, doi: 10.1002/smll.201302825 (2014).Chen Z, Liu Y, Sun B, Li H, Dong J, Zhang L, et al. Poly...
IkappaB kinases: key regulators of the NF-kappaB pathway. The nuclear factor (NF)-kappaB pathway is important for the expression of a wide variety of genes that are involved in the control of the host immune and i... Y Yamamoto,RB Gaynor - 《Trends in Biochemical Sciences》 被引量: 953...
3.6. Protein Expression of Inflammatory Pathway The pulmonary protein expressions related to the inflammatory pathway are presented inFigure 6. Toll-like receptor 4 (TLR-4) (155.43%), myeloid differentiation primary response 88 (MyD88) (146.03%), phosphorylated c-Jun N-terminal kinases (p-JNK) ...