NF-[kappa]B activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65.(Research article)(nuclear factor-[kappa]B)( serine/threonine-specific protein kinase)(Report)Takeshima, ErikoTomimori, KohKawakami, HirochikaIshikawa, Chie...
摘要: PROBLEM TO BE SOLVED: To obtain the subject inhibitor having an NF-κB activation inhibitory activity and useful as a treating agent of an inflammatory disease, an autoimmune disease, a virus disease, a cancer, etc., by containing a specific indolocarbazole derivative....
NF-kappa B activation is required for the transition of pulmonary inflammation to muscle atrophy . Am J Respir Cell Mol Biol . In press... RCJ Langen,A Haegens,JHJ Vernooy,... - 《American Journal of Respiratory Cell & Molecular Biology》 被引量: 82发表: 2012年 NF-κB activation and po...
体伴侣分子1α(peroxisome proliferative activated co-activator activation[J]. Neuroscience, 2011, 30(185): 150-160. [4] Hong JR. Betanodavirus: Mitochondrial disruption and necrotic 1α, PGC1-α), 其中后者是调节清除ROS分子, 如SOD2等的 κ 图2 线粒体介导的免疫炎症反应(摘自文献[21]) PAMPs...
We studied NF-kappa B activation in human breast tumors and in carcinoma cell lines. Activated NF-kappa B was detected predominantly in ER-negative vs. ER-positive breast tumors and mostly in ER-negative and ErbB2-positive tumors (86%). These in vivo results demonstrate association of ...
Genistein inhibits the activation of the kappa light polypeptide gene enhancer in B-cells (NF-魏B), signaling pathway, which is implicated in the balance... M Adjakly,M Ngollo,JP Boiteux,... - 《Anticancer Research》 被引量: 82发表: 2013年 Taylor & Francis Online :: Genistein Inhibits...
NF-kappa B synergizes with NF-AT and NF-IL6 in activation of the IL-4 gene in T cells [J]. Eur J Immunol,2004,34(4) :1111-1118.Li-Weber M.; Giaisi M.; Baumann S.; Palfi K.; Krammer P. H. NF-kappa B synergizes with NF-AT and NF-IL6 in activation of the IL-4 ...
Here, we show that activation of NF-kappaB by ER stress requires an increase in the intracellular levels of both reactive oxygen intermediates (ROIs) and Ca2+. Two distinct intracellular Ca2+ chelators and a panel of structurally unrelated antioxidants prevented NF-kappaB activation by various ER ...
A promoter may or may not be used in conjunction with an “enhancer,” which refers to a cis-acting regulatory sequence involved in the transcriptional activation of a nucleic acid sequence. A promoter may be one naturally associated with a gene or sequence, as may be obtained by isolating ...
Activation of nuclear factor kappa B (NF-κB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic ... R Gao,D Brigstock - 《Cell Communication & Signaling Ccs》 被引量: 0发表: 2005年 Modulation of the nuclear factor-kappa B (NF-κB)...