Down-regulated cylindromatosis enhances NF-κB activation and aggravates inflammation in HBV-ACLF patients Emerging Microbes & Infections(IF:18) 研究发现下调的圆柱状瘤通过增强乙型肝炎病毒相关性急性慢性肝衰竭患者的NF-κB活化来加重炎性细胞趋化性,从而参与HBV-ACFL损伤的发病机制。 Zhang X, Zhang Y, Zho...
Amoebiasis cused by Entamoeba histolytica is still considered amajor health problem in developing countries. In This work (70) serum samples of Patients S uffered from diarrhea and infected with Entamoebahistolytica were examined to evaluate the NF-KB concentration by Elisa method .Recent study ...
[21] Miskolci V,Castro-Alcaraz S,Nguyen P,et al. Okadaic acid induces sustained activation of NFκB and degradation of the nuclear IκBα in human neutrophils[J]. Arch Biochem Biophys, 2003,417(1):44-52. [22] 崔香丹,朱玉今. TNF...
近期,在Science杂志上发表了一篇名为“NF-κB–dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity”的文章,文章中利用单细胞转录组学研究调控肿瘤内cDC1成熟的分子途径,发现核因子kB(NF-kB)和干扰素(IFN)途径在功能成熟的cDC1亚群中高度富集,通过绘制肿瘤内cDC1的成熟轨迹,证明了c...
2. Staudt LM. Oncogenic activation of NF-kappaB. Cold Spring Harb Perspect Biol. 2010;2(6):a000109. doi:10.1101/cshperspect.a000109 3. Pradère JP, Hernandez C, Koppe C, Friedman RA, Luedde T, Schwabe RF. Negative ...
Function : Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter.Subunit :...
independently activating IkBa or IkBb. Another component, A20, a zinc finger protein, is induced by NF-kB activators. A20 acts as a negative regulator, preventing TRAF2 from further activating NF-kB, and it also inhibits TNF and IL-1-induced NF-kB activation, indicating its potent...
27、 in humanmonocytic cells role of NFNFtcBJJJ Immunol,1995;155(2):90290820 Barkett M,Gilmore TDControl of apoptosis by Rel/NFkappa B transcfiptionfactorJOncogene,1999;18:6910692421Weiyu Teng, LishuWang, Weishuang Xue, et a1Activation of TLR4-Mediated NFB Signaling in Hemorrhagic Brain in ...
“Lactucopicrin Inhibits Cytoplasmic Dynein-Mediated NF-kB Activation in Inflammated Macrophages and Alleviates Atherogenesis in Apolipoprotein E-Deficient Mice” Key words: Lactucopicrin;Dynein;NF-kB activation; Inflammated macrophages;Atherogenesis ...
THE BIOLOGY OF A20-BINDING INHIBITORS OF NF-kB ACTIVATION (ABINS) The family of A20-Binding Inhibitors of NF-kB (ABI Isabelle,Carpentier,Lynn,... - 《Advances in Experimental Medicine & Biology》 被引量: 18发表: 2014年 induction of proteasome expression in skeletal muscle is attenuated by ...