Neutrophil extracellular traps (NETs) are a defense mechanism first described to trap and kill bacteria and other pathogens. Increasingly, however, their involvement in the pathogenesis of inflammatory and malignant diseases is being recognized. Several recent studies have suggested important roles of ...
Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at mucosal barriers. However, a dysregulated neutrophil response and, in particular, the excessive release of neutrophil extracellular traps (NETs) are implicated in
PGRP-S colocalize in neutrophil extracellular traps (NETs), suggesting that these granule-derived proteins act together to kill bacteria trapped in the NETs... Cho,H J. - 《Blood》 被引量: 302发表: 2005年 Innate Immune Collectin Surfactant Protein D Simultaneously Binds Both Neutrophil Extracel...
et al. Neutrophil extracellular traps kill bacteria. Science 303, 1532–1535 (2004). This is the first study to describe NETs. CAS PubMed Google Scholar Lood, C. et al. Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like ...
In 2004, NETosis was first reported as an important step to kill bacteria by neutrophils. During the process of NETosis, neutrophil extracellular traps (NETs) that contain large web-like structures of decondensed chromatin decorated with histones and intracellular components, including neutrophil elasta...
Neutrophils release neutrophil extracellular traps (NETs) as part of a healthy host immune response. NETs physically trap and kill pathogens as well as activating and facilitating crosstalk between immune cells and complement. Excessive or inadequately resolved NETs are implicated in the underlying pathoph...
Neutrophil extracellular traps kill bacteria. Science. 2004;303(5663):1532–5. Article CAS PubMed Google Scholar Kim JK, Park MJ, Lee HW, Lee HS, Choi SR, Song YR, et al. The relationship between autophagy, increased neutrophil extracellular traps formation and endothelial dysfunction in ...
Neutrophil extracellular traps kill bacteria. Science 2004 ; 303:1532 - 5; http://dx.doi.org/ 10.1126/science.1092385 ; PMID: 15001782Gregory AD, Houghton AM. Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res 2011 ; 71:2411 - 6; http://dx.doi.org/ 10.1158/0008-...
Neutrophil extracellular traps kill bacteria. Science. 2004;303:1532–5. Article CAS PubMed Google Scholar Dwyer M, Shan Q, D'Ortona S, Maurer R, Mitchell R, Olesen H, et al. Cystic fibrosis sputum DNA has NETosis characteristics and neutrophil extracellular trap release is regulated by ...
et al. Neutrophil extracellular traps kill bacteria. Science 303, 1532–1535 (2004). Article CAS PubMed ADS Google Scholar Kaplan, M. J. & Radic, M. Neutrophil extracellular traps: double-edged swords of innate immunity. J. Immunol. 189, 2689–2695 (2012). Article CAS PubMed Google ...