neutrophil extracellular trap formation通路解释 中性粒细胞外围陷阱形成(neutrophil extracellular trap formation,NETosis)是一种特殊的中性粒细胞死亡方式,用于对抗细菌和其他病原体的感染。 NETosis过程包括以下几个步骤: 1.活化:中性粒细胞受到感染或其他刺激后,会经历一系列内部信号转导事件的激活,包括细胞膜上的...
neutrophilextracellularnovoformationtrap粒细胞 RESEARCHARTICLENeutrophilExtracellularTrapFormationIsIndependentofDeNovoGeneExpressionGabrielSollberger*☯,BorkoAmulic*☯,ArturoZychlinskyDepartmentofCellularMicrobiology,MaxPlanckInstituteforInfectionBiology,Berlin,Germany☯Theseauthorscontributedequallytothiswork.*sollberger@mp...
neutrophilextracellularnovoformationtrap粒细胞 RESEARCHARTICLE NeutrophilExtracellularTrapFormationIs IndependentofDeNovoGeneExpression GabrielSollberger* ☯ ,BorkoAmulic* ☯ ,ArturoZychlinsky DepartmentofCellularMicrobiology,MaxPlanckInstituteforInfectionBiology,Berlin,Germany ☯Theseauthorscontributedequallytothiswork...
Since we had observed that neutrophils and other granulocytes release mitochondrial DNA (mtDNA) in the formation of extracellular DNA traps3, we hypothesized that mitochondrial dynamics might be important for mtDNA release. Five members of the GTPase dynamin family, namely mitofusin-1 (MFN1), mitofusi...
PTH-271Neutrophil extracellular trap formation is increased in patients with colorectal cancer in-vivoIntroductionEmerging evidence suggests that neutrophils, which function as the first line of defence during infections and have been shown to have a multitude of additional roles in immunity, facilitate ...
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J. Cell Biol. 191, 677–691 (2010). CAS PubMed PubMed Central Google Scholar Metzler, K. D. et al. Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate ...
中性粒细胞的一个关键特征是它们能够将一种被称为中性粒细胞胞外陷阱(neutrophil extracellular trap,NET)的结构挤压到周围环境中。NET是一种由被有毒性的酶覆盖的DNA组成的网状结构,正常情况下能够捕获并杀死入侵的微生物。然而,越来越多的证据表明,NET介导了癌细胞侵袭特性的发展和增强,但它们是如何促进癌细胞转移的...
Extracellular traps: how to isolate and quantify extracellular DNA (ET-DNA) A novel rapid Neutrophil Extracellular Trap (NET) release mechanism without neutrophil death [Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps]. ...
Novel Role of IL (Interleukin)-1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic Aneurysms OBJECTIVE: Neutrophils promote experimental abdominal aortic aneurysm (AAA) formation via a mechanism that is independent from MMPs (matrix metalloproteina... AK Meher,M Spinosa,JP Davis,... ...
GermanyNeutrophilextracellulartraps(NETs)havebeenshowntoplayacrucialroleinhealthanddisease.InarecentpaperinPLoSPathogens,Halversonetal.demonstratethattheDNAbackboneofNETscontributestoitsanti-bacterialactivityandservesassignalforentrappedmicrobestoemployimmuneevasionstrategies.In2004,theformationofneutrophilextracellulartraps(...