(redirected from neurokinin receptor antagonist)Also found in: Thesaurus, Medical, Encyclopedia. antagonist a person who opposes another, often in a hostile manner: The man was his antagonist in a duel.; an enemy, foe; the adversary of the hero or protagonist in a literary work Not to be...
The involvement of tachykinin neuropeptides, such as substance P and the neurokinins, in pain transmission is supported by a wealth of evidence. At present. the therapeutic potential of manipulating tachykinin-mediated effects is being investigated and has been assisted by the discovery of several non...
Neurokinin B (NKB) and kisspeptin are obligate for normal gonadotropin secretion, and links between gonadotropin-releasing hormone (GnRH) pulsatility and vasomotor symptoms have been proposed. Using a selective NKB receptor (NK3R) antagonist, the role of NKB in the hypergonadotropic state in ...
文章摘译了Miguel Muñoz等人2020年在Journal of Clinical Medicine期刊上发表的一篇名为The Neurokinin-1 Receptor Antagonist Aprepitant, a New Drug for the Treatment of Hematological Malignancies: Focus on Acute Myeloid Leukemia的文...
Neurokinin receptor antagonist inferior to tolterodine for OABdoi:10.1038/nrurol.2010.105Sarah PaytonNature Reviews Urology
We incubated normal rhesus frontal cortex tissue explants (CNS) and primary cultures of rhesus dorsal root ganglia cells (PNS) with liveB. burgdorferiand tested the effectiveness of the NK1receptor antagonist L703,606 in attenuating inflammatory immune responses and neuronal and glial damage. Culture...
Abstract STUDY QUESTION: Are neurokinin B (NKB), NK3 receptor (NK3R), kisspeptin (KISS1) and kisspeptin receptor (KISS1R) expressed in human ovarian granulosa cells? SUMMARY ANSWER: The NKB/NK3R and kisspeptin/KISS1R systems are co-expressed and functionally active in ovarian granulosa cells...
Female rats treated with the NK3 receptor antagonist SR142801 before mating exhibited a tendency towards decreased fertility with a significant reduction in their litter sizes [55]. In addition, the highest levels of uterine NK3 receptor expression in the pregnant rat (peaking at day 3) are ...
2) Neurokinin B receptor 神经激肽B受体3) neurokinin-1 receptor 神经激肽-1受体 1. Therapeuitc effect of neurokinin-1 receptor s antagonist on lung injury of acute necrotizing pancreatitis; 目的:探讨神经激肽-1受体(NK-1R)拮抗剂对急性坏死性胰腺炎(ANP)大鼠肺损伤的作用,了解ANP时阻断该受体对...
A Neurokinin-1 Receptor (NK1R) antagonist (NK-1RA) that reduces postoperative adhesions reduces the adhesion related chemokines CXCL1(KC) and CXCL2 (MIP-2)... A Neurokinin-1 Receptor (NK1R) antagonist (NK-1RA) that reduces postoperative adhesions reduces the adhesion related chemokines CXCL1(...