Chinolinderivate als neurokininrezeptor-antagonisten Quinoline derivatives as neurokinin receptor antagonistsThe present invention relates to substituted quinoline hydrazides of Formula (I): wherein R 1 , R 2 , R 3 , R 4 , R 5 , X, Y and Z are defined herein, pharmaceutical compositions ...
The present invention is a heteroaromatic substituted amide showing antagonist activity to neurokinin 1 (NK-1, substance P) receptors. Inventors: HOFFMANN TORSTEN (DE) SCHNIDER PATRICK (CH) STADLER HEINZ (CH) Application Number: DE60118569
Piperidinderivate, verwendbar als Neurokinin-Rezeptor-Antagonisten Piperidine derivatives useful as neurokinin receptor antagonistsNanteuil Guillaume DeGeorges RemondBernard PortevinJacqueline BonnetEmmanuel CanetGraham Birrell
N-alkylsubstituierte Piperidin-Derivate mit Neurokinin-Rezeptor antagonistischer Wirkung N-alkyl substituted piperidine derivatives with neurokinin receptor antagonistic activityRobert Toms JacobsAshokkumar Bhikkappa Shenvi
7 - phenyl - 1.4 - diazepanderivate as neurokininrezeptorantagonisten1-Benzoyl-4-aminoacyl-7-phenyl-1,4-diazepine derivatives (I) are new. Also new are four classes of intermediates. 1,4-Diazepine derivatives of formula (I) and their acid addition salts are new. Ph1 = phenyl substituted ...
1-Benzoyl-4-carbamoyl-2-indolylmethyl-piperazine derivatives (I) are new. Piperazine derivatives of formula (I) and their acid addition salts are new. R1 = H or lower alkyl; R2 = H or halo; R3 = H or lower alkoxy. An Independent claim is given for the preparation of (I).JASSERAND...
1,3,8-TRIAZA-SPIROi4,5 DECAN-4-ONDERIVATIVE ALS NEUROKININREZEPTORANTAGONISTENThe invention relates to compounds of the formulaas described herein and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor.GALLEY GUIDO...
1,3,8 - triaza - spiroi4,5 decan - 4 - onderivative as neurokininrezeptorantagonistenThe invention relates to compounds of the formulaas described herein and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor.GALLEY, GUIDO...
1,3,8-TRIAZA-SPIROi4,5 DECAN-4-ONDERIVATIVE AS NEUROKININREZEPTORANTAGONISTENThe invention relates to compounds of the formulaas described herein and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor....