NEPC (neuroendocrine prostate cancer) 神经内分泌前列腺癌 PCa (prostate cancer) 前列腺癌 molecular signature database (MSigDB) 定义了已知基因集,包括H和C1-C7八个系列(Collection/cluster) image.png ONECUT2 is a potential master transcriptional regulator of poorly differentiated neuroendocrine tumors 数据来源...
Neuroendocrine prostate cancer (NEPC), also referred clinically to as anaplastic prostate cancer or small cell carcinoma of the prostate, is a lethal, androgen receptor (AR)-negative variant that most commonly arises from treated adenocarcinoma of the prostate. NEPC does not respond to AR-directed ...
Neuroendocrine prostate cancer (NEPC) encompasses various clinical contexts, ranging from the de novo presentation of small cell prostatic carcinoma to a treatment-emergent transformed phenotype that arises from typical adenocarcinoma of the prostate. The development of resistance to potent androgen receptor...
1 术语? NEPC-neuroendocrine prostate cancer 神经内分泌前列腺癌 PCa-prostate cancer 前列腺癌 t-NEPC-treatment-emergent NEPC (t-NEPC) hypoxia-directed therapy 2 数据 PCa Beltran data set ---All BAM files and associated sample information are described in Supplementary Table 11; data are deposited i...
Molecular mechanisms of neuroendocrine differentiation in prostate cancer progression Journal of Cancer Research and Clinical Oncology - Rapid evolution of the therapeutic management of prostate cancer, especially in in second-generation and... Y Xie,S Ning,J Hu - 《Journal of Cancer Research & ...
Neuroendocrine (NE) cells are found in prostate tumors, and their incidence is considered a promising prognostic indicator for the development of androgen-independent disease. NE cells are derived from non-NE prostate cancer cells and secrete factors that can act in a paracrine manner to stimulate ...
Neuroendocrine cells in tumour growth of the prostate. Endocr Relat Cancer. 1999; 6 (4):503–519.Abrahamsson PA. Neuroendocrine cells in tumour growth ... Abrahamsson,P. - 《Endocr Relat Cancer》 被引量: 518发表: 1999年 Neuroendocrine expression in metastatic prostate cancer: evaluation of hi...
Neuroendocrine prostate cancer (NEPC) is a highly aggressive histologic subtype of prostate cancer associated with a poor prognosis. Its incidence is expected to increase as castration-resistant disease emerges from the widespread use of potent androgen receptor-targeting therapies, such as abiraterone and...
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