Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands Shengli Zhang & Giovanni Maglia Department of Chemistry, University of Oxford, Oxford, UK Yujia Qing & Hagan Bayley Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University ...
The invention discloses a detection method for biomolecular probe-calibrated specific sites of DNA based on a nanopore device and application thereof. The method comprises the following steps: 1) calibrating the specific sites of DNA by using a biomolecular probe so as to obtain calibrated DNA; ...
Nanochannel Device with Embedded Nanopore: a New Approach for Single-Molecule DNA Analysis and ManipulationNanopore and nanochannel based devices are robust methods for biomolecular sensing and single DNA manipulation. Nanopore-based DNA sensing... Y Zhang,W Reisner - 《American Physical Society》 被引...
Third, nanopores provide a well-defined scaffold for controllably designing and constructing biomimetic systems, which involve a complex network of biomolecular interactions. These nanopore systems track the binding dynamics of transported biomolecules as they interact with nanopore surfaces, hence serving as...
Nanopores as single-molecule biosensors were initially developed for ultrasensitive DNA sequencing and other label-free biomolecular sensing techniques1,2,3,4,5. They register geometrically confined single molecules that bind within or translocate through their interior volumes to allow label-free sensing6...
Novel Materials and Devices for Biomolecular Characterization Front Matter Pages 209-209 Download chapterPDF Novel Materials and Devices for Bio-Molecular Characterization Graphene Nanopore Devices for DNA Sensing Chris A. Merchant, Marija Drndić ...
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The synergy of life sciences discoveries, biomolecular and protein engineering advances, and groundbreaking nanofabrication technologies, has introduced over the past years the wide use of the nanopore‐based investigations of matter at the molecular level. This review focuses on the fundamental principles...
according to their nanoporous materials. We begin with a brief description of the translocation-based detection mechanism of nanopores. Next, specific examples are given in nanopore-based nucleic acid analysis and sequencing, with an emphasis on identifying strategies that can improve the resolution of...