Background and Purpose-After stroke, the population of infiltrated neutrophils in the brain is heterogeneous, including a population of alternative neutrophils (N2) that express M2 phenotype markers. We explored the role of TLR4 (toll-like receptor 4) on neutrophil infiltration and polarization in ...
while iNOS+CD16b+ cells were considered to be N2-type TANs.26 In three patients with serum CXCL9 levels below the ULC and three patients with serum CXCL9 levels above the 2x ULC, we noticed that higher serum CXCL9 levels were associated with more N1 neutrophil infiltration, further confirmin...
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, et al. Polarization of tumor-associated neutrophil phenotype by TGF- beta: ``N1'' versus ``N2'' TAN. Cancer Cell. 2009;16:183--94.Fridlender, Z. G., Sun, J., Kim, S., Kapoor, V., Cheng, G., Ling, L., Worth...
markers neutrophil gelatinase-associated lipocalin and kidney injury molecule 1, as well as functional kidney parameters.ConclusionHyperpolarized functional 13C,15N2 urea MRI can be used to successfully detect changes in the intrarenal urea gradient post-IRI, thereby enabling in viv...