NEUTROPHILSThis letter, published in the Archives of Dermatological Research, discusses a pilot study that aimed to explore the role of low-density neutrophils (LDNs) in hidradenitis suppurativa (HS), a chronic skin disease. The study found that HS patients had a significantly higher frequency of ...
Low-density neutrophils (LDNs) have been described in tumors and various autoimmune diseases, where they exhibit immune dysfunction and alter disease progression. Nevertheless, LDNs have been rarely reported in sepsis. We studied sepsis patients admitted to the intensive care unit. Wright-Giemsa stain ...
Low-density neutrophils (LDNs) are a subset of neutrophils first described in the bloodstream upon pathological conditions, and recently, in the blood of healthy humans. LDNs may have an enhanced pro-inflammatory (low-density granulocytes, LDGs) or an immunosuppressive (Granulocytic myeloid-derived ...
Neutrophils are phenotypically heterogeneous and exert either anti- or pro-metastatic functions. We show that cancer-cell-derived G-CSF is necessary, but not sufficient, to mobilize immature low-density neutrophils (iLDNs) that promote liver metastasis. In contrast, mature high-density neutrophils inh...
NWC indicates Normal Weight Control; MOP, Morbidly Obese Patient; N represents the total number of participants evaluated; n/N, fraction of the population with specific characteristic; BMI, body mass index; LDN, low-density neutrophils. Values are shown as n/N (%), median with 25 and 75 ...
Low-density neutrophils (LDNs) have been described in tumors and various autoimmune diseases, where they exhibit immune dysfunction and alter disease progression. Nevertheless, LDNs have been rarely reported in sepsis. We studied sepsis patients admitted to the intensive care unit. Wright-Giemsa stain...
Neutrophils are the earliest white blood cells that accumulate in the kidney after renal injury and are the major contributing factor to further renal injury after reperfusion by releasing ROS, proteases, elastase, and cationic peptides [43]. Neutrophils secrete chemokines and pro-inflammatory cytokines...
Inhibition of low-density lipoprotein oxidation and oxidative burst in polymorphonuclear neutrophils by caffeic acid and hispidin derivatives isolated from sword brake fern (Pteris ensiformis Burm.). Wei Hsiu-An,Lian Tzi-Wei,Tu Yi-Chen,Hong Jing-Ting,Kou Mei-Chun,Wu Ming-Ji...
The effect on neutrophils is likely to account for the reduction in NLR ratio, a reliable marker of inflammation, observed at week 12. Importantly, CRP plasma levels were also significantly reduced at all time points in VLCKD group, confirming the anti-inflammatory effects of this dietary ...
(1991) Membrane surface antigen expression on neutrophils: a reappraisal of the use of surface markers for neutrophil activation. Blood 78: 1105–1111. [17] Martin-Martin B, Nabokina SM, Blasi J, Lazo PA, Mollinedo F (2000) Involvement of SNAP-23 and syntaxin 6 in human neutrophil ...