A tumor profiling assay that tests for far more mutations than any other test has received authorization from the US Food and Drug Administration (FDA). The product, developed at the Memorial Sloan Kettering (MSK) Cancer Center in New York City, is known asMSK-IMPACT(MSK-Integrated Mutation ...
However, hybridisation capture is a labour-intensive and time-consuming enrichment assay that includes overnight probe hybridisation and, given the limitations of short-read sequencing, samples must then be batched, resulting in lengthy turnaround times. Furthermore, any updates to c...
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.The identification of specific genetic alterations as key oncogenic drivers and the development of ...
Framework to process and call somatic variation from NGS dataset generated using MSK-IMPACT assay ngs cancer-genomics cancer-variants illumina-sequencing precision-medicine msk-impact mskimpact Updated Mar 29, 2021 Perl Improve this page Add a description, image, and links to the msk-impact top...
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. Journal of Molecular DiagnosticsCheng DT, Mitchell TN, Zehir A, Shah RH, Benayed R, Syed A, ...
et al. Memorial Sloan Kettering-integrated mutation profiling of actionable cancer targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. J. Mol. Diagn. 17, 251–264 (2015). Article CAS Google Scholar Zehir, A. et al....
IMPACT-Pipeline: MSK-IMPACT assay data analysis framework to process data on LSF/SGE Author: Ronak H Shah, Donavan Cheng, Ahmet Zehir, Aijazuddin Syed, Raghu Chandramohan, Meera Prasad et.al Contact: rons.shah@gmail.com Source code: http://github.com/rhshah/IMPACT-Pipeline Wiki: http://...
Is Next Generation Sequencing (NGS) Ready for Routine Clinical Practice in Gliomas? Results of a Prospective Study Utilizing the MSK-IMPACT Assay 喜欢 0 阅读量: 11 作者: AMP Omuro,A Zehir,DT Cheng,MF Berger,DM Hyman,DB Solit,J Baselga,M Ladanyi,ME Arcila,M Hameed 展开 ...
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK- IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. J Mol Diagn. 2015;17:251-64.Cheng DT, Mitchell TN, Zehir A, Shah RH, Benay...
MSK-IMPACT: A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. Cheng DT, Mitchell TN, Zehir A, Shah RH, Benayed R, Syed A, et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridiz...