发现MSK-IMPACT能够重现已知胚系检测结果(with both inter- and intra- run replicates),并在16例样本中发现了新的致病性突变。 强调了NGS gene panel全面鉴定癌症易感性相关胚系突变(SNVs、InDels、large deletions或duplications、SVs)的适用性和重要性,NGS gene panel可以同时检测体细胞水平变异和胚系变异。 已知233...
发现MSK-IMPACT能够重现已知胚系检测结果(with both inter- and intra- run replicates),并在16例样本中发现了新的致病性突变。 强调了NGS gene panel全面鉴定癌症易感性相关胚系突变(SNVs、InDels、large deletions或duplications、SVs)的适用性和重要性,NGS gene panel可以同时检测体细胞水平变异和胚系变异。 已知233...
noting its potential for‘other smaller entities with less infrastructure than MSK’. Beyond MSK-IMPACT, Stephanie noted, the method could be adapted for use with‘any gene panel’for a simple, highly customisable
发现MSK-IMPACT能够重现已知胚系检测结果(with both inter- and intra- run replicates),并在16例样本中发现了新的致病性突变。强调了NGS gene panel全面鉴定癌症易感性相关胚系突变(SNVs、InDels、large deletions或duplications、SVs)的适用性和重要性,NGS gene panel可以同时检测体细胞水平变异和胚系变异。 已知233例...
The evolutionary impact of childhood cancer on the human gene pool Ulrik Kristoffer Stoltze Jon Foss-Skiftesvik Kjeld Schmiegelow Nature Communications (2024) Germline functional variants contribute to somatic mutation and outcomes in neuroblastoma Eun Seop Seo Ji Won Lee Woong-Yang Park Nature ...
Core members were selected to include specialists in areas relevant to the impact of cancer in minority communities, deans and area leaders with broad reach and awareness of faculty activities within their respective institutions, as well as scholars with experience in programs to mentor and train ...