产品名称 :Recombinant Mouse GLP1R 货号:P-Db1476 宿主:E.Coli 标签:N-terminal His Tag 规格: 50μg, 200μg, 1mg 种属:Mouse 表达区间:22-145 分子量:13.5 kDa 纯度:Greater than 95% as determined by SDS-PAGE 应用:Western Blot, ELISA ...
Here, we investigated the contribution of lipolytic and oxidative changes in white adipose tissue (WAT) to the weight-lowering effect induced by the GLP-1 receptor (GLP-1R) agonist exenatide (exendin-4) in mice. We also looked at the role of SIRT1 in this process. METHODS: C57BL/6J ...
HEK293 cells (5×104) are seeded in a 96-well plate and transiently cotransfected with the GLP-1R plasmid and the CRE-luciferase reporter plasmid. After a 48 h transfection, different concentrations of GLP-1(1–37) or GLP-1(7–37) are added, and the cells are incubated for 5 h. Th...
1), to examine the genome-wide expression changes in glial and neurovascular cells in aging, and their modulation by GLP-1R agonism. We calculated significant differentially expressed genes (DEGs) (defined as those with false discovery rate (FDR)-adjusted P-value < 0.05) for each cell type, ...
该小鼠胰高血糖素样肽 1 受体,GLP1R GENLISA™ ELISA试剂盒产品的样本类型:血清、细胞培养物上清液和血浆检测范围是:Please refer to the current IFU for the updated calibrator range and sensitivity.产品特点 该小鼠胰高血糖素样肽 1 受体,GLP1R GENLISA™ ELISA试剂盒产品的检测方法:比色法,450nm保存建...
GLP-1 (9-36) retained its glucagonostatic effects after genetic/pharmacological inactivation of the GLP-1 receptor. GLP-1 (9-36) also potently inhibited glucagon secretion evoked by p-adrenergic stimulation, amino acids and membrane depolarisation. In islet alpha cells, GLP-1(9-36) led to ...
Notably, the expression of marker genes for other pancreatic cells, such as Ins, Nkx6.1 and Glp1R (β-cells), Sst (δ-cells), were similar in iAlpha cells and TTFs (P40.05; Figure 2b). Furthermore, the expression of the δ cell-specific gene, Sst, was 50-fold lower in iAlpha ...
the response to GLP-1R activation is different [95]. A new transcriptomics tool visualizing Glp1r mRNA expression in the brain between men and women from 20 to 70 years old shows that later in life, women have greater expression than men [96]. However, whether IRA receptors play a role ...
GLP-1R 胰高糖素样肽-1受体抗体 规格: 0.1mlFLIP/c FLIP 凋亡调节基因之一抗体 规格: 0.1ml奇任 英文名称:Kirenol 规格::HPLC≥98% 20mg/支 保存::-20℃,避光 phospho-DAG1 (Tyr892) 磷酸化肌萎相关蛋白DAG1抗体 规格: 0.1mlSarcosine 肌氨酸 100g 瓶 ...
Here we explore the role of the bed nucleus of the stria terminalis (BNST), an area involved in feeding control as well as stress responses, in GLP-1 responses. Using cre-expressing mice we visualized projections of NTS PPG neurons and GLP-1R-expressing BNST cells with AAV-driven ...