Programmed death ligand 1 gene silencing in murine glioma models reveals cell line-specific modulation of tumor growth in vivo. Evelina Blomberg et al. Neuro-oncology advances, 4(1), vdac148-vdac148 (2022-10-11) Glioblastoma is the most common brain tumor in adults and virtually incurable. ...
The enzyme was not inducible in any mouse neuroblastoma cells or in other glioblastoma cell lines such as G26-15. The results on the mouse glioblastoma cell lines G26-20 and 24 (which exhibit a number of properties characteristic of immature glial cells) suggest a possible role for ...
Cell culture supernatants from primary glioblastoma cell lines were cleared of cellular debris and dead cells by centrifugation, and vesicles were partitioned by filtering through consecutively smaller pore-sized filters (2 μm, 0.8 μm, 0.22 μm, 0.02 μm) and free protein complexes were ...
After adaptive feeding for 7 days, mice were ran domly allocated to two groups (vehicle- and TMZ-treated groups; n=6/group) and underwent intracranial GL261-cell implantation and subsequent vehicle or TMZ gavage. The mouse glioblastoma cell line GL261 was obtained from the American Type ...
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects. Nature Genet. 26, 109–113 (2000). CAS PubMed Google Scholar Silberg, D. G. et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology 122, 689–696 (2002). ...
as well as inhibited the expression of antiviral factors in C6 glioblastoma cell line. Furthermore, HddSBL downregulated the expression levels of histone H3 and H4, and upregulated histone H3R8 and H4R3 asymmetric dimethylation, confirming the effect of HddSBL on chromatin structure suggested by ...
We identified clusters in expression of genes involved in cellular proliferation, as well as molecular markers for glioblastoma that were significantly downregulated in tumors of MNF-treated mice as compared to saline-injected controls. The efficacy of MNF against C6 glioma cell proliferation in vivo ...
1c,d). A significant reduction of cell viability was observed at 6–48 h after SDT. Figure 1 Cell viability by sonodynamic therapy (SDT) in mouse glioma stem cells (GSCs). (a) Changes of luminescence images and intensity in human glioblastoma U251 cells for 12 h after treatment with 1...
Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci USA 2011; 108: 4274–4280. 21 Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell ...
Sample: A172 human glioblastoma cell line fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005) Knockout Validated Vimentin is specifically detected in K562 human chronic myelogenous leukemia parental cell ...