The mouse neuroblastoma tumor line C1300, clone Neuro-2a, can proliferate in a serum-free synthetic medium supplemented with insulin, transferring, progesterone, selenium and putrescine (N2 medium), with a marked increase in cell number as compared to the optimal 10% serum containing medium. More...
In this work, we show that the N1E-115 mouse neuroblastoma cell line rapidly responds to melatonin stimulation and forms neurites within 24 h. We also demonstrate that these cells readily bind 2-[125I]iodomelatonin at levels consistent with what is noted for native tissues (Bmax=3.43±1.56 ...
Virus Res 232:1-5. https://doi.org/10.1016/j .virusres.2017.01.011.Thunuguntla P, El-mayet FS, Jones C. 2017. Bovine herpesvirus 1 can efficiently 968 infect the human (SH-SY5Y) but not the mouse neuroblastoma cell line (Neuro- 969 2A). Virus Res 232:1-5....
Clones of Pigo-knockout (KO) Neuro2a, a mouse neuroblastoma cell line, were generated by CRISPR–Cas9 system. Each Pigo mutant cDNA (R119W, T130N, K1051E) driven by a strong promoter, SRα, was transfected into Pigo-KO Neuro2a cells by Lipofectamin 2000 (Invitrogen) together with luc...
The mouse neuroblastoma cell line (N2a cells) is a commonly used cell line whose differentiation and neurite outgrowth can be induced by RA[30, 31]. In N2a cells, RA treatment in combination with a lower concentration of serum (1%) induced cell differentiation and neurite outgrowth, ...
TheDmTMEM63 protein is related to three mammalian TMEM63 proteins (Fig.6a). In search for a system to examine the functions of mammalian TMEM63 proteins, we screened several cell lines and found Neuro-2a (N2a) cells, a mouse neuroblastoma cell line, showed high-level expression of endogenou...
NeuroblastomaN1E-115* OropharyngealmEER PancreaticPan02* PlasmacytomaJ558 RenalRenca* SarcomaEHS, Meth A TeratomaF9_FR * Lines that are available with profile Get a Price PK/PD Studies In addition, pharmacological effects and pharmacokinetics of test compounds can be determined in the ...
Chromosome studies were carried out in cultured cells from a mouse neuroblastoma. C1300 tissue and in three clones established from this tumor. They possessed characteristic karyotypes with remarkable markers. Double minutes (DMs) were demonstrated in all cell lines, in addition to some other chromos...
To investigate the apoptotic effect of prion peptide PrP106-126 on mouse neuroblastoma cell line,N2a,a flow cytometry assessment with Annexin V-FITC/PI and apoptotic morphology were used to detect apoptosis induced by PrP106-126.The results showed that 15,25 and 50 μmol/L at 24 h substan...
Zeng, M. & Zhou, J. N. Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells.Cell Signal.20, 659–665 (2008). ArticleCASGoogle Scholar Levine, B. & Kroemer, G. Biological functions of autophagy genes: a disease perspective.Cell176, 11–42 (2019)....