Macrophages and monocytes display high functional plasticity, altering their phenotype and activity in response to changing conditions within their microenvironment.A feature of advancing age is elevated basal levels of proinflammatory cytokines and other indicators of chronic inflammation, a phenomenon termed...
必应词典为您提供monocytes-and-macrophages的释义,网络释义: 单核巨噬细胞;单核球及巨噬细胞;
(MPS). A term introduced by Van Furth that encompasses myeloid immune cells other than polymorphonuclear granulocytes and initially included monocytes and macrophages, and then, following their discovery, dendritic cells. microRNA (miRNA). A class of short endogenous non-coding RNAs that modulate the...
W. (1977) Monocytes and Macrophages in Malignant Melanoma. I. Peripheral Blood Macrophage Precursors. Br. J. Cancer, 36, 1.Currie, E. A., and Hedley, G. W. Monocytes and macrophages in malignant melanoma. Peripheral blood macrophage precursors. Br. J. Cancer, 36: 1- 6, 1977....
Our understanding of the ontogeny of monocytes and macrophages, as well as their maintenance in the steady state, has recently undergone a renaissance. Here, Ginhoux and Jung discuss the evidence that has changed our view of the relationship between mono
Monocytes and Macrophages Rheumatoid arthritis (RA) is a disease characterized by an inflammatory response within the joint resulting in cartilage and bone destruction. Infiltratio... S Nares,SM Wahl - Humana Press 被引量: 51发表: 2000年 Origin of osteoclasts: mature monocytes and macrophages are...
Studies with glucocorticoids, both in vitro and in vivo, demonstrate complex actions of these mediators on monocytes and macrophages and highlight the importance of the mononuclear phagocyte system in determining lung homeostasis and induction of the disease process....
Monocytes and macrophages are part of the body's first line of defense, eliminating pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as cytokines, chemokines and proteases. In humans, three subsets of monocytes are described with seemingly different functions. ...
To develop a simple and efficient method for producing homogeneous populations of monocytes and macrophages from human embryonic stem cells (hES). Materials and Methods Human embryonic stem cell lines KCL001, KCL002, and HUES-2 were differentiated into monocytes by coculture-free differentiation with...
macrophages and monocytes, skewing their responses to injury or infection. Cell-inherent age-associated alterations in functional potential are superimposed on these changes within the tissue milieu. Here we discuss the phagocytic mononuclear cell populations of two tissues, the heart and lungs, their ...