We will focus on monocytes; however, since monocyte function is interlinked with that of macrophages and dendritic cells, the latter populations will also be discussed. We will highlight the role of monocytes in the context of individual diseases and discuss how therapeutics impact them. Finally, ...
Tumour-derived microvesicles (TMVs) are important players in tumour progression, modulating biological activity of immune cells e.g. lymphocytes, monocytes and macrophages. This phenomenon is particularly interesting in the progression of colon cancer, a
In silico analyses predicted GRP78, which is constitutively expressed on monocytes and macrophages, to be a potential candidate receptor for SARS-CoV-2 virus entry. Methods Hospitalized COVID-19 patients were characterized regarding their pro-inflammatory state and cell surface GRP78 (csGRP78) ...
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The difference between pneumocysts opsonized in untreated versus complement-depleted serum was not significant (10.7 versus 12.6 fmol/cell per 90 min). Monocyte-derived macrophages also activated the respiratory burst when stimulated with pneumocysts, and this effect could be significantly increased, ...
Although increased serum leptin has previously been linked to modulation of innate immunity, we found no significant difference in the LPS stimulated production of TNF-alpha by either blood monocytes or alveolar macrophages between the dietary groups. Furthermore, we failed to find a significant ...
macrophages and monocytes are permissive for 青云英语翻译 请在下面的文本框内输入文字,然后点击开始翻译按钮进行翻译,如果您看不到结果,请重新翻译! 翻译结果1翻译结果2翻译结果3翻译结果4翻译结果5 翻译结果1复制译文编辑译文朗读译文返回顶部 翻译结果2复制译文编辑译文朗读译文返回顶部...
This mechanism and its effects should be investigated in further human immune cell populations, such as monocytes and macrophages, in respect of TLR7 but also TLR8. A relevant study in mice has recently identified a robust sexual dimorphism in tissue macrophages [79] by using transcriptome and ...
The ontogeny of macrophages varies in different tissues, such that some tissue resident macrophages are seeded embryonically and self-renew in a similar manner to stem cells, whereas other macrophages (such as in the dermis or gut) are continually replenished by blood-derived monocytes2–6. ...
[29,30,31,33,34,35,39,64,65,66]. GCase, the enzyme encoded by the PD-genetic risk factorGBA, is important for the metabolic processes of scavenger cells such as monocytes and macrophages. Compared to previous works that performed unbiased transcriptomic analysis comparing PD and CTRL ...