Monocyte-derived dendritic cells (moDCs) are increasingly used in clinical settings to stimulate tumor immunity. Prostaglandin E2 (PGE2), which is a member of the eicosanoid family of oxygenated arachidonic acid derivatives generated through the action of cyclooxygenases (COXs), is frequently used ...
Monocyte-derived dendritic cellsTTPmRNA stabilityThe chemokine CXCL4 has been implicated in several immune diseases. Exposure of monocyte-derived dendritic cells (moDCs) to CXCL4 potentiates the production of inflammatory cytokines in the presence of TLR3 or TLR7/8 agonists. Here we investigated the...
Monocyte-derived dendritic cellsThromboelastometryThe crosstalk between immune and coagulation systems plays pivotal roles in host defense, which may involve monocyte-derived dendritic cells (moDCs). Our objectives were to elucidate the role of moDCs in coagulation under inflammatory conditions and the ...
Recently, the cytochrome P‐450 enzymes expressed in monocyte-derived dendritic cells (MoDCs) were characterized. In the present study, N-acetyltransferase 1 and 2 (NAT-1 and -2) mRNA expression and N-acetylation capacities of these cells were investigated. Monocytes from healthy donors were ...
Blocking monocyte entry into the lymph node and tumor through neutralization of the chemokine CCL2 or inhibition of colony-stimulating factor-1 receptor signaling prevented the generation of moDCs, the infiltration of tumor-specific T cells into the tumor, and antitumor responses. In a reciprocal ...
In this study we set out to evaluate the effects of 1,25-(OH)2D3 on the phenotype of cattle monocyte-derived dendritic cells (MoDCs) and how the conditioning with this vitamin affects the function of these myeloid cells. Results MoDCs were generated from CD14+ monocytes with bovine IL-4...
结论:Hp感染状态不影响胃癌患者外周血MoDCs成熟过程形态变化,Hp感染的胃癌患者MoDCs成熟和活化水平更高。关键词树突状细胞幽门螺杆菌胃癌doi:10.3969/j.issn.1000-8179.2013.15.006EffectofHelicobacterpylorionthefunctionofperipheralbloodmonocyte-deriveddendriticcellsingastriccancerpatientsQiaozhenLI1,YuqiangCHEN1,Jianghua...
Statins inhibit iNOS‐mediated microbicidal potential of activated monocyte‐derived dendritic cells by an IFN‐β‐dependent mechanism[J] . Pilar M. Domínguez,María López‐Bravo,Ulrich Kalinke,Carlos Ardavín.Eur. J. Immunol. . 2011 (11)...
In this study we analyzed the permissiveness of human peripheral blood mononuclear cells (PBMCs) including monocyte-derived dendritic cells (moDCs) to CCHFV infection. Interestingly, we found that moDCs are the most permissive to CCHFV infection and this infection induced cytokine release from moDCs...
In this study, the effect of caffeic acid phenethyl ester (CAPE), the most extensively studied components in propolis, on the functions of human monocyte-derived dendritic cells (MoDCs) was investigated. Results CAPE significantly inhibited IL-12 p40, IL-12 p70, IL-10 protein expression in ...