Lao et al., "Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells," Journal of Leukocyte Biology, vol. 101, no. 4, pp. 901-911, 2017.Rudloff I, Cho SX, Lao JC, Ngo D, McKenzie M, Nold‑Petry CA and Nold MF: Monocytes...
Their granules contain enzymes that damage or digest pathogens and release inflammatory mediators into the bloodstream. Mononuclear leukocytes include lymphocytes, monocytes, macrophages, and dendritic cells. This group is involved in both innate and adaptive immune system function. What kind of cell is ...
To perform their cellular function, T cells need to be activated by antigen-presenting cells, such as dendritic cells (DCs). The aim of this work was to analyze DC differentiation and activation from monocytes of HTLV-1-infected individuals. We demonstrated that monocytes from HTLV-1-infected ...
Monocytes Which of the following cells ejects it's nucleus during development? A) reticulocyte A) basophilic erythroblast C) erythrocyte D) normoblast Which leukocyte(s) contain a large, U-shaped nucleus? What is the other term that a mature dendritic cell can be known by? (Hint: morphology...
Dendritic cells (DC) generated after a short-term exposure of monocytes to IFN-alpha and GM-CSF (IFN-DC) are highly effective in inducing cross-priming of CD8(+ )T cells against viral antigens. We have investigated the mechanisms responsible for the special attitude of these DC and compared...
A) monocytes B) basophils C) lymphocytes D) neutrophilsWhat cell types would you find in the thymus?Fill in the blank: The type of leukocytes involved with immunity (B-cells and T-cells) are collectively referred to as ___.Which adaptive...
Sapp M, Engelmayer J, Larsson M, Granelli-Piperno A, Steinman R, Bhardwaj N. Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses. Immunol Lett. 1999;66:121-128....
CD137 ligand (CD137L) signaling has been used to derive a novel type of DCs from human peripheral blood monocytes, termed CD137L-DCs. Here, we report that CD137L-DCs induce more potent cytotoxic T-cell responses than classical DCs (cDCs). Furthermore, in exploring several DC maturation ...
cells and is necessary for uptake and transfer to CD4 T cells11,32,33,34,44,45,46,51. Furthermore we have shown blocking the ability of HIV to bind both DC-SIGN and mannose receptor on MDDCs derived in vitro from blood CD14+monocytes significantly blocks HIV uptake11,12. However, we...
cytometry of bone marrow-derived (CD45(+ve)) cell populations at 24 h post-IRI demonstrated that F4/80(+ve)/CD11c(+ve) DCs remained proportionately stable and exhibit higher levels of DC maturation markers, whereas the proportion of F4/80(-ve) DCs, monocytes, neutrophils, and T cells ...