Immunology The role of C1q in regulation of monocyte to dendritic cell differentiation| Implications in autoimmunity STATE UNIVERSITY OF NEW YORK AT STONY BROOK Berhane Ghebrehiwet HosszuKinga KGrowing evidence shows that the first component of complement, C1q, regulates the growth and function of ...
Faculty Opinions recommendation of CD137 ligand signaling induces human monocyte to dendritic cell differentiation. P Romero,M Braun 被引量: 0发表: 2010年 CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells ...
Figure 5.Refrigeration of Leukopaks Preserves Monocyte-to-Dendritic Cell Differentiation Ability for Up to 5 Days Using EasySep™ Human Monocyte Isolation Kit (Catalog #19359), monocytes were isolated from 1 leukopak fraction (Catalog #70500) of each storage condition daily for 5 days, and 1 ...
The maturation of harvested DCs on day seven was evaluated via flow cytometry, a beta-counter and an ELISA kit."n"nResults: This study showed that the endothelial cells interact with dendritic cells generated from peripheral blood monocytes via cell-to-cell interaction. This interaction inhibits ...
Culture supernatants from Mel-RhS interfered with monocyte-to- dendritic-cell differentiation, leading to the development of M2-like macrophages, which was in part prevented by antibody- mediated IL-10 blockade. Indeed, high-dimensional single-cell analysis revealed a shift within the monocyte ...
Collectively, the hLF1–11 peptide drives monocyte-DC differentiation toward DCs that promote antifungal responses and enhance Th17 polarization. 展开 关键词: Dendritic cell Monocytes Antimicrobial peptide T lymphocyte Polarization <italic>Candida albicans</italic> ...
Differentiation into other effector cells As known, monocytes can differentiate either into macrophages or dendritic cells, depending upon the milieu. In case of infection, macrophages get differentiated into- Macrophages,for the purpose of eliminating the microbes by phagocytosis. Replenishing the resident...
Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Mesenchymal stem cells (MSCs), in addition to their multilineage differentiation, have a direct immunosuppressive effect on T-cell proliferation in vitro. ... Xiao-Xia,Jiang,Yi,... - 《Blood》 被...
Human monocytes cultured in stiff, elastic hydrogels show proinflammatory polarization and differentiation towards dendritic cells, as opposed to those cultured in a viscoelastic matrix. This mechanically induced cell differentiation is blocked by inhibiting a myeloid-specific isoform of phosphoinositide 3-...
Refer to Table 1 for volumes required for other types of cultureware. Table 1. Recommended Volumes of ImmunoCult™ DC Differentiation Medium for Various Cultureware Cultureware Volume of ImmunoCult™-ACF Dendritic Cell Medium Number of Cells/Well 96-well plate 100 µL/well 1 x 105 24-...