Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response. J.Leukoc.Biol. 2006;80:555-562.Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 ...
To elucidate the potential in vitro effects of this drug on human monocyte-derived DC, we used low nanomolar therapeutic concentrations of FTY720 and phosphorylated FTY720 (FTY720-P) and investigated their influence on DC surface marker expression, protein levels of S1PR and DC effector functions: ...
22. We also previously showed that HIV transfer to CD4 T cells occurs in two successive phases from epidermal LCs13, epidermal CD11c+DCs21and in vitro derived monocyte-derived (MDDC)17,23. The first phase of transfer occurs within 2 h and is dependent on lectin mediated uptake...
Since CD38 is expressed by resting monocytes, we aimed to monitor CD38 expression during the differentiation of human monocyte-derived DC (MDDC) and to investigate the possibility that CD38 plays a functional role during DC maturation. CD38 is down-modulated during differentiation into immature MDDC...
Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (TH2) or TH1/TH2 effectors. Role of stimulator/responder ratio. J. Exp. Med. 192, 405–412 (2000). CAS PubMed PubMed Central Google Scholar Kalinski, P., Schuitemaker, J. H., Hilke...
Larsen and colleagues47 recently compared the effects of airway commensals and pathogenic bacteria on human monocyte-derived DCs, reporting that pathogenic bacteria provoke considerably higher IL-23, IL-12p70, and IL-10 production than commensal bacteria, such as Prevotella species and Veillonella ...
The most eminent use of monocytes isolated by MACS® Technology is theirex vivodifferentiation into monocyte-derived dendritic cells (Mo-DCs). The excellent purity and recovery obtained by using CD14 MicroBeads provide a pure and consistent cell source (fig. 1). Contamination with unwanted cells ...
Shigella flexneri infection of macrophages (MΦ) leads to activation of caspase-1 by the IpaB virulence factor, which induces rapid cell death and release of mature IL-1β. Herewe show that S. flexneri infection of human monocyte-derived dendritic cells (DC) also results in rapid IpaB-depen...
In this study, the effect of caffeic acid phenethyl ester (CAPE), the most extensively studied components in propolis, on the functions of human monocyte-derived dendritic cells (MoDCs) was investigated. Results CAPE significantly inhibited IL-12 p40, IL-12 p70, IL-10 protein expression in ...
Lymphoid tissue and plasmacytoid dendritic cells and macrophages do not share a common macrophage–dendritic cell-restricted progenitor. Immunity 41, 104–115 (2014). Article CAS PubMed Google Scholar Liu, Z. et al. Fate mapping via Ms4a3-expression history traces monocyte-derived cells. Cell ...