GNL = galanthus nivalis lectin, EBL = elderberry bark lectin/sambucus nigra agglutinin; HPA = helix pomatia agglutinin, VVL = vicia villosa lectin, DBA = dolichol biflorous agglutinin, A4 = mAb A4, α-Lex = anti-Lewis X antibody, α-H = anti-H type...
Here we describe a monoclonal antibody, 2G1, that neutralizes all current VOCs and has surprising tolerance to mutations adjacent to or within its interaction epitope. Cryo-electron microscopy structure showed that 2G1 bound to the tip of receptor binding domain (RBD) of spike protein with small...
Keywords: IDH1; R132H; novel rabbit monoclonal antibody; B-cell cloning; immunohistochemistry 1. Introduction Isocitrate dehydrogenase 1 (IDH1) functions as an enzyme in the Krebs (citric acid) cycle and is biologically active in the cytoplasmic and peroxisomal compartments under normal conditions [1...