While receiving clozapine, if the patient develops fever and symptoms of flu, the dose of clozapine should be reduced to about half to avoid clozapine toxicity and can be later optimized. Clozapine levels can be done, depending on availability (Siskind et al., 2020). It is also known that ...
CLOZAPINEDRUG monitoringAGRANULOCYTOSISANTIPSYCHOTIC agentsPATIENT safetyExtending the frequency of full blood count monitoring of patients receiving clozapine from every 4 weeks to every 12 weeks resulted in no increase in hematological adverse events, a one‐year study has found. The results len...
While clozapine is reported to be an effective therapy for treatment-resis... MS Morris,T Hogan,A Mcguire - 《Clinical Drug Investigation》 被引量: 26发表: 1998年 [Cost-effectiveness analysis of schizophrenic patient care settings: impact of an atypical antipsychotic under long-acting injection ...
1.Wantourtreatmentstowork2.Donotwishtreatmentstocauseharm.Monitoringdrugtreatmentisonewayofseeingthatatreatmentworks,whileprotectingthepatientfromadversedrugeffects.Formanypatientsandmanytreatmentsclinicalevaluationissufficient(e.g.Measuringbloodpressureinapatientonantihypertensivetreatment).Whentherapeuticgoalscannotalwaysbe...
Will Routine Therapeutic Drug Monitoring Have a Place in Clozapine Therapy?Will Routine Therapeutic Drug Monitoring Have a Place in Clozapine Therapy?HumansClozapineAntipsychotic AgentsDrug InteractionsClinical Trials as TopicBiological AvailabilityDrug MonitoringClozapine...
A Puzzling Case of Increased Serum Clozapine Levels in a Patient With Inflammation and Infection Espnes, Ketil ArneHeimdal, Kent OveSpigset, Olav 489-492 False-Positive Amphetamine/Ecstasy (MDMA/3,4-Methylenedioxymethamphetamine) (CEDIA) and Ecstasy (MDMA/3,4-Methylenedioxymethamphetamine) (DRI) Tes...
Impact of Pharmacogenetic Testing on Clozapine Treatment Efficacy in Patients with Treatment-Resistant Schizophrenia INDIVIDUALIZED medicinePATIENT monitoringManaging schizophrenia with clozapine poses a significant challenge due to prevalent therapeutic failures. The increasing ... E Sangüesa,E Fernández-Egea,...
Its role in therapy varies depending on the drug being prescribed... SH Preskorn,MJ Burke,GA Fast - 《Psychiatric Clinics of North America》 被引量: 141发表: 1993年 Adverse drug reaction monitoring in psychiatry out-patient department of an Indian teaching hospital. Objectives: Adverse drug rea...
It is illustrated for a patient on long-term treatment, who displayed an unexpectedly high clozapine concentration after the introduction of ciprofloxacin comedication. The prospective on and off comedication panel study shows advantages in terms of carefully selected inclusion criteria and control of ...
Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry. 2003;60(1):82–91. doi:10./archpsy682PubMed 11. Ellenberg SS, Myers MW, Blackwelder WC, et al. The use of external monitoring committees in clinical trials of the ...