探究miRNA-132（miR-132）通过Hedgehog 信号通路对肝细胞癌细胞凋亡的机制。方法：用miR-132类似物转染人肝癌HepG2细胞，将样本分为空白组（无转染HepG2）、NC 组（HepG2转染miR-132-NC ）、YJ 组（HepG2转染miR-132 mimic ）。通过qRT-PCR 检测miR-132在HepG2细胞中的表达量，采用CCK-8法、流 式细胞...
The pro-atherosclerotic effect of AT-EX is associated with the MiR-132/212-GNA12/PTEN signaling in vitro.ANormalized atherosclerosis-related miRNA levels in SAT-EX and VAT-EX.BThe potential target genes of the miR-132/212 cluster were predicted by bioinformatic analysis.CG protein subunit alpha...
在本研究表明,在联合治疗中,超声波强度越大,miRNA⁃132和miRNA⁃34a表达水平越低,神经病理性疼痛发生发展的活跃性会受到抑制,这或许与联合治疗可最大限度刺激miRNA⁃132和miRNA⁃34a表达水平的降低有关。其可能的机制是下调miRNA⁃...
Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the development of heart failure, one of the leading medical causes of mortality worldwide. Here we show that the microRNA (miRNA)-212/132 family regulates cardiac hypertrophy
MiRNA-155 and miRNA-132 as potential diagnostic biomarkers for pulmonary tuberculosis: A preliminary study 喜欢 0 阅读量: 34 作者:ML Zheng,NK Zhou,CH Luo 摘要: In our study, we aimed to profile a panel microRNA 关键词: Pulmonary tuberculosis Differentially expressed microRNAs Mycobacterium ...
摘要: •A total of 38 differentially expressed miRNAs were identified based on FDR < 0.01.•MiRNA-155 obtained the highest AUC value 0.976.•MiRNA-155, and miRNA-132 appeared in 50 and 48 bootstraps.关键词: Pulmonary tuberculosis Differentially expressed microRNAs Mycobacterium tuberculosis...
上海第十人民医院:脂肪来源干细胞分泌外泌体通过调节miRNA-132/TGF-β途径促进淋巴管生成 淋巴管生成在炎症性肠病(IBD)的发病机制中起重要作用,血管内皮生长因子-C(VEGF-C)是一种强大的淋巴管生成因子。脂肪来源的干细胞(ADSCs)可以分泌生长因子和外泌体,调节受疾病影响的恶劣微环境。然而,外泌体对VEGF-C依赖...
miRNA-132/212 Deficiency Disrupts Selective Corticosterone Modulation of Dorsal vs. Ventral Hippocampal Metaplasticity. Int. J. Mol. Sci. 2023, 24, 9565. https://doi.org/10.3390/ ijms24119565 Academic Editor: Giuseppina Martella Received: 8 May 2023 Revised: 21 May 2023 Accepted: 25 May 2023 ...
miRNA-132/212 Deficiency Disrupts Selective Corticosterone Modulation of Dorsal vs. Ventral Hippocampal Metaplasticity by Shima Kouhnavardi 1, Maureen Cabatic 1,†, M. Carmen Mañas-Padilla 2,†, Marife-Astrid Malabanan 1, Tarik Smani 3, Ana Cicvaric 1,4, Edison Alejandro Mu...