15.6 MicroRNA-132 As we discussed earlier miR-132 is another critical miRNA for synaptic function. MiR-132 is one of the most abundant brain-enriched miRNAs shown to regulate neuron morphogenesis and plasticity [103]. MiR-132 level was found to be is significantly reduced in the brains of AD...
MicroRNA-132 Central nervous system (CNS) Oxidative stress Neuronal apoptosis Acetylcholinesterase (AchE) Brain-derived neurotrophic factor (BDNF) 1. Introduction MicroRNAs (miRNAs), as pivotal regulators of gene expression, participate in a wide range of biological processes and contribute to the pathog...
there wasmiR-132down regulation in cervical cancer. There was also a direct association between the levels ofmiR-132expressions and radiation intensity.MiR-132increased radio sensitivity throughBMI-1targeting [78]. It has been shown that there was significantmiR-132down regulation in SKOV3/CDDP cel...
MicroRNA-132 targets PEA-15 and suppresses the progression of astrocytoma in vitro 来自 EBSCO 喜欢 0 阅读量: 44 作者:F Geng,JL Wu,GF Lu,ZP Liang,ZL Duan,X Gu 摘要: Gliomas are highly malignant tumors, the most common of which are astrocytomas. A growing number of studies suggest that...
Cancer as one of the leading causes of human deaths has always been one of the main health challenges in the world. Despite recent advances in therapeutic and diagnostic methods, there is still a high mortality rate among cancer patients. Late diagnosis
microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice 来自 Semantic Scholar 喜欢 0 阅读量: 53 作者: J Hernandez-Rapp,S Rainone,C Goupil,V Dorval,PY Smith,M Saint-Pierre,M Vallée,E Planel,A Droit,F Calon 展开 ...
microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disease triple transgenic mice Julia Hernandez-Rapp, Sara Rainone, Claudia Goupil, Véronique Dorval, Pascal Y. Smith, Martine Saint-Pierre, Maxime Vallée, Emmanuel Planel, Arnaud Droit, ...
www.nature.com/scientificreports OPEN received: 08 June 2016 accepted: 11 July 2016 Published: 03 August 2016 microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice Julia Hernandez-Rapp1,2,*, Sara Rainone1,2,*, ...
Altered Expression Levels of MicroRNA-132 and Nurr1 in Peripheral Blood of Parkinson's Disease: Potential Disease Biomarkers. 来自 NCBI 喜欢 0 阅读量: 68 作者:Zhaofei,Yang,Tianbai,Li,Song,Min,Wei,Hongqian,Qi,Bairong 摘要: MicroRNAs (miRNAs) are small and evolutionary conserved noncoding RNAs...