以上结果表明,在CAP信号肽的引导下,MSCsSC的工程外泌体显著提高了外泌体miR-199a-3p对软骨细胞的递送效率,并显示出软骨细胞自噬的增强,从而在OA细胞模型中具有治疗潜力。 8.在体内通过工程MSCsSC-Exos介导软骨靶向miR-199a-3p的...
miR-199a-3p 生物信息学 mTOR GO富集分析 KEGG Pathway分析 膀胱癌 PI3K-Akt MAPK 蛋白聚糖目的为深入研究miR-199a-3p在膀胱癌形成和发展中的作用提供理论依据。方法分析miR-199a-3p序列,预测其靶基因和转录因子,并对靶基因进行GO富集和KEGG Pathway分析;构建TF-miR-199a-3p-靶基因网络调控图。结果 miR-199a...
bta-miR-199a-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:bta-miR-199a-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:bta-miR-199a-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对...
5.如权利要求1所述的miR-199a-3p在失重诱导心脏重塑防治药物中的用途,其特征在于,所述药物的剂型包括注射液、口服剂。 6.如权利要求1所述的miR-199a-3p在失重诱导心脏重塑防治药物中的用途,其特征在于,所述药物的封装包括脂质体封装、纳米颗粒封装、微胶囊封装、肠溶衣封装、树突状大分子封装。
货号:ipu-miR-199a-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:ipu-miR-199a-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制...
MicroRNAs (miRNA) have rapidly emerged as modulators of gene expression in cancer in which they may have great diagnostic and therapeutic import. MicroRNA-199a-3p (miR-199a-3p) is downregulated in several human malignancies including hepatocellular carcinoma (HCC). Here, we show that miR-199a-...
miR-199a-3p在制备抗乙型肝炎病毒药物中的应用,所述miR-199a-3p为序列表SEQIDNO:1所述的核苷酸序列。 实验结果表明:miR-199a-3p能有效地降低HBsAg表达,但不影响HepG22.2.15细胞的增殖。实时PCR对HBVDNA定量显示miR-199a-3p抑制病毒的复制。生物信息学分析表明在HBsAg编码区有miR-199a-3p的结合位点,通过荧光报...
mml-miR-199a-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:mml-miR-199a-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:mml-miR-199a-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对...
There are comments on PubPeer for publication: <p>Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer</p> (2020)
It has been shown that miR-199a-3p was significantly down-regulated in several types of cancers. However, its role and relevance in renal cell carcinoma (RCC) are still largely unknown. Here, we show that miR-199a-3p is significantly down-regulated in human RCC primary tumors and cell ...