骨转移前列腺癌中mir-19a-3p表达量更低,按前列腺癌组织中mir-19a-3p表达量的中位值将患者划分为mir-19a-3p低表达组和mir-19a-3p高表达组,统计mir-19a-3p表达量与前列腺癌患者骨转移状态的病例数,如图1b所示,前列腺癌骨转移患者中,mir-19a-3p低表达比例高于mir-19a-3p高表达比例,而前列腺癌无骨转移患者中,m...
Moreover, over-expression of miR-19a-3p or silencing of IGFBP3 expression promoted activation of AKT, which is important for aerobic glycolysis in cancer cells, indicating that miR-19a-3p promotes aerobic glycolysis in ovarian cancer cells through the IGFBP3/PI3K/AKT pathway. ...
答:研究组的miR-19a-3p表达明显高于对照组,并且miR-19a-3p在结直肠癌(CRC)患者血清中高表达0.001; B:研究组的FOXF2(FOXF2)表达明显低于对照组,并且FOXF2在大肠癌患者中表达较低0.001; C:miR-19a-3p曲线下面积为0.883;D:FOXF2曲线...
一项刊登在影响因子3041的杂志oncologyreports上题为downregulationofmir19a3ppromotesinvasionmigrationandbonemetastasisviaactivatingtgfsignalinginprostatecancer的研究报告中来自遵义医学院附属医院的研究者们发现mir19a3p促进前列腺癌骨转移的机制这将有助于开发有效的前列腺癌治疗方法 遵义医学院发现miR-19a-3p促进前列腺癌骨...
mml-miR-19a-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:mml-miR-19a-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:mml-miR-19a-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
货号:dre-miR-19a-3p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:dre-miR-19a-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
Interestingly, there was a significant change in miR-19a-3p, whose target gene is known to be associated with MEF2 signaling. However, whether and how SFI regulates miR-19a-3p in the treatment of myocardial hypertrophy has not been investigated. The purpose of the present study was to ...
本发明公开了miR19a3p在制备前列腺癌骨转移诊断试剂和治疗药物中的应用.本发明研究发现miR19a3p在前列腺癌骨转移中低表达,且miR19a3p低表达与前列腺癌骨转移相关,过表达miR19a3p能在体外抑制骨转移前列腺癌迁移和侵袭,在体内抑制前列腺癌骨转移,以上结果表明,miR19a3p可应用于制备前列腺癌骨转移诊断试剂,治疗药物中.收...
内皮细胞功能障碍是川崎病冠状动脉病变的重要因素,也是川崎病恢复期的一个显著特征,但其发病机制尚不清楚.微小RNA(microRNA,miRNA)已被广泛报道与KD的发病机制密切相关.目前研究表明,与非KD发热对照组相比,miR-210-3p,miR-184和miR-19a-3p在KD组中表达显著上调.然而,这些上调的循环miRNA在内皮功能障碍中的潜在作用...
Objective. miR-19a-3p is widely increased in several cancers and can be used as an oncogenic factor in these cancers. However, the molecular mechanism of miR-19a-3p in bladder urothelial carcinoma (B...