而过表达miR-379-5可以抑制细胞内游离胆固醇的含量和改善线粒体功能;抑制高脂高胆固醇饮食诱导的 db/db 小鼠的肝体比、血清ALT和AST,缓解饮食诱导的肝损伤。随后的分子机制研究中,采用蛋白质谱分析、生物信息学预测及一系列分子/细胞生物学技术阐明了miR-379-5p是通过下调STAT1/HMGCS1轴发挥缓解游离胆固醇蓄积的作用...
Conclusion: miR-379-5p in OSCC regulates the proliferation, cell cycle, and DDP resistance of tumor cells by targeting ROR1. Keywords: Oral squamous cell carcinoma, miR-379-5p, ROR1, DDP resistanceLei MengYanlin DuBanglian DengYinzhong Duan...
英文名称:hsa-miR-379-5p mimic 品牌厂商性质产地货期价格 MedChemExpress (MCE)生产商美国现货￥960 性能特点 hsa-miR-379-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 在线咨询
chi-miR-379-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:chi-miR-379-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:chi-miR-379-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
miR-379-5pexpression levels were detected by real-time quanti-tative polymerase chain reaction (RT-qPCR) andGlucose regulated protein 78 (GRP78) protein levelwas measured by western blot assay. Interactionsbetween LINC00665 and miR-379-5p or betweenmiR-379-5p and GRP78 were verif i ed by ...
LINC00665 promotes breast cancer progression by regulating the miR-379-5p/LIN28B axis Fig. 6: The clinical relevance of LINC00665, miR-379-5p, and LIN28B expression in breast cancer. Full size image Discussion In the current study, we showed that LINC00665 functions as an oncogene in breas...
目的探讨骨髓增生异常综合征(MDS)患者血清miR-125b-5p,miR-17-5p表达变化及其与临床特征和预后的关系.方法选择MDS患者76例(MDS组),健康志愿者32例(对照组),采集所有研... 姜铭,徐娟,贲海祥,... - 《山东医药》 被引量: 0发表: 2023年 miR-125a-3p 和 miR-17-5p 在激素性股骨头坏死中的作用 目的:...
MiR-379-5pSEMA3Aexperimental autoimmune uveitisUveitis is a disease resulting in the inflammation of uveal tracts, but the factors resulting in uveitis is still obscure. Previous studies have shown that miR-379-5p was involved in the pathogenesis of several diseases, however, the role and ...
MiR-379–5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT)Baoyi Yang aShitao Xia aXiangmei Ye bWei Jing aBeifeng Wu a
增殖侵袭迁移目的 通过研究miR-379-5p对小鼠乳腺癌4T1细胞增殖,侵袭和迁移的影响,为临床抑制乳腺癌增殖,侵袭和转移提供新的治疗靶点.方法 采用实时荧光定量聚合酶链反应(real-time fluorescence quantitative polymerase chain reaction, qRT-PCR)检测miR-379-5p在质粒转染后4T1细胞中的表达情况;采用5-乙炔基-2'脱氧...