In addition, the inhibition of CRC cell stemness caused by PF was eliminated by miR-3194-5p overexpression. CTNNBIP1 functioned as the target of miR-3194-5p, whose knockdown abrogated the repression of CRC cell stemness and Wnt/尾-catenin signaling activation by PF.PF regulated...
Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progressionCD44Estradiol (E2)Lung cancerRNF4Sp1microRNAsBackground:Sp1, an important transcription factor, is involved in the progression of various cancers. Our previous studies have ...