miR-3184-5pEGFR化疗耐药研究背景与目的 骨肉瘤是最常见的恶性骨肿瘤,常发生在四肢干骺端,如股骨远端和胫骨近端.由于其高度的侵袭性,大约有10%到15%的新诊断转移性疾病出现,这使得五年生存率从60%降低到20%,极大地影响了患者的临床预后.目前,治疗方法包括手术和新辅助化疗,但转移患者的生存率和化疗耐药性仍然...
Mechanistically, FOXP4-AS1 post-transcriptionally regulated FOXP4 by acting as a competing endogenous RNA (ceRNA) in PCa to sponge miR-3184-5p. Considering the upregulation of both FOXP4-AS1 and its nearby gene FOXP4, we further detected the coactivator of FOXP4-AS1 and FOXP4. Mechanism ...
CircEMBmiR-3184-5pEGFRChemoresistanceOsteosarcoma (OSA) is the most prevalent type of bone cancer with a high rate of metastasis. Circular RNAs (CircRNAs) play an essential role in multiple aspects of tumour biology. This study aimed to elucidate the role of circEMB in OSA.#circRNAs related ...
Genome‐wide analysis reveals miR‐3184‐5p and miR‐181c‐3p as a critical regulator for adipocytes‐associated breast cancerdoi:10.1002/jcp.28428Rajarajan, DheeranSelvarajan, SweethaCharan Raja, Mamilla R.Kar Mahapatra, SantanuKasiappan, Ravi...