采用实时荧光定量PCR检测各组miR-328-5p表达情况,采用CCK-8实验及平板克隆形成实验检测miR-328-5p对各组细胞增殖能力的影响,采用细胞划痕实验检测miR-328-5p对各组细胞迁移能力的影响,采用Transwell体外细胞侵袭实验检测miR-328-5p对各组细胞侵袭能力的影响.结果乳腺癌细胞系MCF-7,MDA-MB-231中miR-328-5p相对表达...
Actually, miR-328-5p promoted the malignant behaviors of HCC cells, while DAB2IP had opposite effects. Moreover, circRNA-5692 overexpression inhibited the growth of xenograft HCC tumors in vivo by decreasing miR-328-5p expression to enhance DAB2IP expression. In conclusion, the circRNA-5692–miR-...
目的探究miR-328-5p通过调节自噬影响乳腺癌细胞对紫杉醇(Taxol)化疗敏感性的作用机制.方法选取乳腺癌MCF-7细胞为研究对象,根据目的不同分为miR-NC组(转染阴性对照),miR-328-5p组(转染miR-328-5p mimics),miR-NC+Taxol组和miR-328-5p+Taxol组,以及si-NC组(转染阴性对照),si-整合素α5(ITGA5)组(转染si-IT...
中miR-328-5p相对表达量明显降低,SPON2相对表达量明显升高(均P<0.05);与正常组比较,胃癌组胃组织中p-FAK,p-Src蛋白表达水平均明显升高(均P<0.05).与NC,miR-con组比较,miR-328-5p组miR-328-5p相对表达量明显升高,同时Vimentin,MMP-9相对表达量均明显降低(均P<0.05);与NC,miR-con组比较,miR-328-5p组...
Actually, miR-328-5p promoted the malignant behaviors of HCC cells, while DAB2IP had opposite effects. Moreover, circRNA-5692 overexpression inhibited the growth of xenograft HCC tumors in vivo by decreasing miR-328-5p expression to enhance DAB2IP expression. In conclusion, the circRNA-5692鈥搈iR...
Correction for: LncRNA LOC146880 promotes esophageal squamous cell carcinoma progression via miR-328-5p/FSCN1/MAPK axiscorrectionThis article has been corrected: The authors recently found errors in Figure 2. The images for the Si-LOC146880 1# (Kyse30) and Si-LOC146880 2# (Kyse30) on top ...
miR-328-5pE2F1tumor growthIncreasing studies indicated that circular RNAs (circRNAs) play important roles in cancer progression. However, the roles of circRNAs in colorectal cancer (CRC) remain largely unkn... 查看全部>>Chi ZhouHua-shan Liu...
用实时荧光定量PCR法检测高压氧治疗前(T1)及高压氧治疗1个月后(T2),患者血清miR-3195,miR-328-5p和miR-6867-5p的表达水平;通过受试者工作特征(ROC)曲线和Logistic回归分析评估这3种指标对创伤性脑损伤患者高压氧治疗预后的评价效能及其与预后的关系.结果预后良好组患者的格拉斯哥昏迷评分(GCS)高于预后不良组,发病...