结果:癲痫患者血浆外泌体miR-197-5p的表达量低于健康对照组,两者比较差异具有统计学意义;不同病程癫痫患者血浆外泌体miR-197-5p含量具有显著性差异,病程时间越长,其血浆外泌体miR-197-5p的含量则越低,血浆外泌体miR-197-5p的表达水平与患者癩痫严重程度呈负相关.结论:血浆外泌体miR-197-5p有望成为评价癫痫...
英文名称:hsa-miR-197-5p mimic 品牌厂商性质产地货期价格 MedChemExpress (MCE)生产商美国现货￥960 性能特点 hsa-miR-197-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 在线咨询
The transient overexpression of miR-197-5p causes a significant decrease in viability and proliferation of fibrosarcoma cells in both concentration- and time-dependent manners. Interestingly, we did not observe any significant changes in cellcycle pattern or apoptotic cell populations, but rather noticed...
杂志俱乐部 2024年第 45 期 LncRNA HOTAIR modulates chondrocyte apoptosis and inflammation in osteoarthritis via regulating miR-1277-5p/SGTB axis 期刊:Wound Repair Regen 年/期/卷/页:2021 May; 29(3): 495-504杂志俱乐部22...
1.首次确定导致ITP骨髓MSCs凋亡的关键miRNA,即miR-98-5p; 2. miR-98-5p靶向调控IGF2BP1促进ITP骨髓MSCs凋亡; 3. miR-98-5p靶向IGF2BP1,其介导的下游IGF-2/PI3K通路抑制和p53上调参与ITP骨髓MSCs的凋亡调控; 4. 全反式维甲酸(ATRA...
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miR-197-5p increases Doxorubicin-mediated anticancer cytotoxicity of HT1080 fibrosarcoma cells by decreasing drug effluxNeha JainBasudeb DasBibekanand Mallick
Our data demonstrated upregulation of circ0125803 promotes the neuroblastoma progression by blocking miR-197-5p and upregulating E2F1 expression. CONCLUSION :This study uncovered the biological function of the circ0125803-miR-197-5p-E2F1 axis in neuroblastoma metastasis and growth. Copyright 2022. ...
Only miR-197-5P correlated with fibrosis as seen in cardiac magnetic resonance imaging in patients under the age of 50 years with stage C or D HF (r = 0.42, p = 0.008). Multivariate analyses revealed that miR-197-5P was also a risk factor for composite endpoint events in patients under...
Only miR-197-5P correlated with fibrosis as seen in cardiac magnetic resonance imaging in patients under the age of 50 years with stage C or D HF (r = 0.42, p = 0.008). Multivariate analyses revealed that miR-197-5P was also a risk factor for composite endpoint events in patients under...