这些实验都表明circTLK1作为miR-136-5p的海绵。 5.miR-136-5p通过靶向CBX4促进肾癌进展 为了确定miR-136-5p的潜在基因,我们利用TargetScan、miRDB、Starbase和miRTarBase数据库进行了生物信息学分析,选择CBX4、GNAS、LUZP6、MSL2、MTMR4和SOCS7作为miR136-5p的潜在靶点(图5a)。进一步的综合转录分析表明miR-136-5p表...
这些实验都表明circTLK1作为miR-136-5p的海绵。 5.miR-136-5p通过靶向CBX4促进肾癌进展 为了确定miR-136-5p的潜在基因,我们利用TargetScan、miRDB、Starbase和miRTarBase数据库进行了生物信息学分析,选择CBX4、GNAS、LUZP6、MSL2、MTMR4和SOCS7作为miR136-5...
hsa-mir-136-5p RT-PCR检测试剂盒 英文名称: hsa-mir-136-5p RT-PCR Detection Kit 品牌: Abbexa 货号: abx096110 规格: 50 rxns 价格: $362.5 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 试剂和工具 试剂...
肾癌miR-136-5pP4HB增殖迁移侵袭目的 观察miR-136-5p对肾癌细胞增殖,迁移和侵袭的影响并探究其机制.方法 运用实时荧光定量聚合酶链反应(real-time fluorescence quantitative polymerase chain reaction,RT-qPCR)法检测肾癌组织和肾癌细胞中miR-136-5p,脯氨酰4-羟化酶,β-多肽(Prolyl 4-hydroxylase,β-polypeptide,P4...
chi-miR-136-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:chi-miR-136-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:chi-miR-136-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
In addition, PlncRNA-1 modulated the expression of smad3 and has-miR-136-5p (miR-136). Conversely, miR-136 regulated the expression of PlncRNA-1 and smad3. PlncRNA-1 mimics competitive endogenous RNA (ceRNA) in its regulation of smad3 expression by binding miR-136. Rescue analysis ...
In conclusion, we intended to reveal that TJ-M2010-5 up-regulated miR-136-5p levels, changing the imbalance in anti-inflammatory regulation induced by the MyD88 promoter methylation and alleviating inflammatory responses by involving the PI3K/AKT3 pathway....
To identify potential targets of miR-136-5p, we compared its sequence to the mouse genome database. The results showed that the 3′ UTR region of AKT3 contained potential binding sites for the miR-136-5p sequence (Figure5A). Thus, we transfected miR‐136-5p mimics into HEK 293 T cells...
spiralis in its early stages by blocking the activation of PI3K/miR-136-5p/AKT3. 展开 关键词: TJ-M2010-5 MyD88 inflammation Trichinella spiralis methylation DOI: 10.1186/s13567-025-01459-2 年份: 2025 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Springer EBSCO 相似文献MyD88 inhibitor TJ...
由于旁分泌信号在此过程中的重要性,因此从DP细胞培养物中分离出了分泌组和外泌体,并研究了它们的治疗效果。证明了miR-218-5p在DP球体来源的外泌体中明显上调。Western印迹和免疫荧光成像被用来证明DP球体衍生的外泌体上调了β-caten...