Involvement of miR-133a and miR-326 in ADM resistance of HepG2 through modulating expression of abcc1. J Drug Target. 2015;25:1–6.Involvement of miR-133a and miR-326 in ADM resistance of HepG2 through modulating expression of ABCC1[J] . Jin Ma,Ting Wang,Rui Guo,Xiaoyan Yang,Jie ...
miR-133a与miR-326靶向ABCC1对HepG2药物敏感性的影响 目的:探讨miR-133a,miR-326对肝癌HepG2细胞5-氟尿嘧啶,阿霉素和顺铂化疗药物敏感性的影响及作用机制. 方法:生物信息学软件预测ABCC1基因3′UTR潜在的miRNA结合位点;双... 马锦 - 《南华大学》 被引量: 1发表: 2014年 MicroRNA-328 Negatively Regulates...
Wei-Wei Shen,Zhi Zeng,Wen-Xia Zhu,Guo-Hui Fu.MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells[J]. Journal of Molecular Medicine .2013(8)SHEN W W, ZENG Z, ZHU W X, et al. MiR-142-3p func- tions as a tumor suppressor by...
MiR-34a的表达是通过包含多个规范的p53结合基序的MIR34AHG基因启动子附近的区域由p53调控的。由于miPEP133的ORF作为miR-34a pri-miRNAs的一部分与miR-34前光标相邻(图1a),我们推测miPEP133的表达也受到p53通过MIR34AHG启动子的调控。为了验证...
本文拟构建人miR-133重组腺病毒,研究其在人骨髓间充质干细胞(hMSCs)中的表达。方法从人基因组DNA中扩增包含miR-133的PCR产物,并定向插入腺病毒穿梭载体pAdTrack-CMV。将经pmeⅠ线性化的重组穿梭载体与腺病毒骨架质粒pAdEasy-1共转化感受态大肠杆菌BJ5183,通过同源重组获得重组腺病毒质粒rAd-mir-133。rAd-mir-133在...
MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells. J Mol Med (Berl). 2013. : 10.1007/s00109-013-1037-x .Shen WW,Zeng Z,Zhu WX,et al.MiR-142-3p functions as a tumor suppressor by targeting CD133,ABCG2,and Lgr5 in colon ...
This report,"Mandible exosomal ssc-mir-133b regulates tooth development in miniature swine via endogenous apoptosis" by Li et al. is an important step forward in describing the factors that control tooth development in a large animal model. That many of the regulatory miRNA pathways have been ...