Background: We estimated the prevalence and incidence of amyloid-尾 deposition (A), small-vessel disease (V), and neurodegeneration (N) biomarker positivity in community-dwelling cognitively normal individuals (CN). We determined the longitudinal association between the respective biom...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
The added value of embedding retinal image analytics in cross-linked health datasets to study SVD is yet to be determined; this requires intra-individual change detection in stratified prospective cohorts to be tracked. As a cross-sectional study, we can only determine associations not causation, ...
amygdala, parahippocampal, fusiform, inferior temporal, and middle temporal cortical regions; mean ± SD.bMean11C-PiB PET uptake in each group at baseline, two-year follow-up, and longitudinal change. The mean uptake was
and treatment received. A comprehensive neurological examination was performed, and the following tests were administered: the Spanish version of the Mini-Mental State Examination test28, the Hachinski Ischemic Scale29, the Global Deterioration Scale30, the Geriatric Depression Scale31, the Clinical Demen...
Association Between Traumatic Brain Injury (TBI) and Cerebral Small Vessel Disease (SVD) eTable 4. Association Between Traumatic Brain Injury (TBI) and Clinical Features Supplement 2. Nonauthor Collaborators Supplement 3. Data Sharing Statement 1. Livingston G, Huntley J, Somme...
It remains unclear whether lowering the blood pressure effectively prevents cognitive impairment. The aim of the current study was to explore the association between the prevalence, treatment and control of hypertension and the risk of mild cognitive imp
Ischemic brain lesions associated with hypertension (HTN). HTN induces atherosclerosis of major extracranial and intracranial arteries, which could lead to major infarcts. HTN causes both microbleeds and macrobleeds and is the main pathogenetic factor for small vessel disease responsible for lacunar ...
Twenty-Four Hours of Mild Hypothermia in Unsedated Newborn Pigs Starting after a Severe Global Hypoxic-Ischemic Insult Is Not Neuroprotective MARIANNE THORESEN, SAULIUS SATAS, ELSE MARIT LØBERG, ANDREW WHITELAW, DOMINIQUE ACOLET, CARL LINDGREN, JULIET PENRICE, NICOLA ROBERTSON, EGIL HAUG, AND ...
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