Only a small percentage of these released cells are efficient and capable of colonizing with a strong metastatic potential. CMCs' ability to survive in circulation express a variety of genes with continuous changes of signal pathways and proteins to escape immune surveillance. This makes it difficult...
which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third...
49Invasion is stimulated by increased activity of Wnt 5a and Notch pathways (increased expression of transcription factors Twist and Snail) and activation of PKC causing cytoskeletal changes that enhance cell motility.49,50Twist, in particular, has an essential role in inhibiting E-CAD...
method of standardizing the extent of change assessed via one measure enabled comparisons between two measures. An ES of 1.0 is equivalent to a change of one standard deviation in the sample. Effect sizes of 0.2, 0.5, and 0.8 are typically considered small, medium, and large changes, ...