The article titled "Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis" by Stefanie Grabrucker et al. explores the impact of microbiota from Alzheimer's patients on cognition and neurogenesis in the hippocampus. The authors apologize for an ...
Alzheimer’s patients had a higher abundance of inflammation-promoting bacteria in fecal samples, and these changes were directly associated with their cognitive status. Professor Yvonne Nolan said: “The memory tests we investigated rely on the growth of new nerve cells in the hippocampus region of...
Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis. Brain. 2023;146:4916–34. Article PubMed PubMed Central Google Scholar Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, et al. Gut microbiota regulate motor deficits and ...
discussed. We likewise address the role of GM in neurodegenerative diseases such as Parkinson’s and Alzheimer’s, and its possible therapeutic use, taking advantage of the fact that centenarians are characterized by an extreme (healthy) phenotype versus patients suffering from age-related pathologies....
Recently, attempts have been also made to apply FMT to the treatment of such diseases as metabolic syndrome, diabetes, Crohn's disease, Parkinson's disease, multiple sclerosis, psoriasis, anorexia nervosa or Alzheimer disease [17]. The aim of this review was to present the most current ...
The systemic inflammation caused by gut dysbiosis triggers the disruption of the blood-brain barrier (BBB) and contributes to pathogenesis of neurodegenerative disorders, such as Alzheimer’s disease [13], Parkinson’s disease [14], and multiple sclerosis [15]. This disruption facilitates the passag...
2.2. Gut microbiota composition differences in relationship to sex during childhood (from 1 to 12 years) In the first 12 months of life, the infant’s intestine undergoes changes due to solid food introduction in the diet with a consequent variation of the microflora (Stark and Lee, 1982). ...
[61]. For example, they have mutual communication with the brain called as gut–brain axis. Enteric nervous system and the central nervous system both are under influence of them. Thereby, they partake in several CNS diseases like Parkinson’s disease, Alzheimer’s disease [62], schizophrenia ...
The possible role of lytic phages in the induction of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases or amyotrophic lateral sclerosis was documented. Patients who have Parkinson’s disease showed 10-fold higher concentrations ofLactococcus lytic phages with a severe reduction ...
Alzheimer’s disease (AD) is a prevalent and progressive neurodegenerative disorder that is the leading cause of dementia. The underlying mechanisms of AD have not yet been completely explored. Neuroinflammation, an inflammatory response mediated by certain mediators, has been exhibited to play a cruci...