为了评估MHCIIhi中性粒细胞与MHCIIlow中性粒细胞的功能，作者通过流式分选从荷瘤小鼠中分离出中性粒细胞，通过Transwell实验表明，MHCIIhi和MHCIIlow中性粒细胞都可以促进肿瘤细胞迁移和侵袭，且MHCIIhi中性粒细胞对肿瘤迁移的影响更大。RNA-seq和流式细胞术结果显示，MHCIIhi和MHCIIlow中性粒细胞都高表达ROS相关基因...
Increased CD11cHIMHCIIHI DCs in H. pylori–infected mouse stomach and the expression of TLRs by H. pylori-stimulated BMDCs.Xia, SunMin, ZhangMohamad, ElZataariStephanie, Y. OwyangKathryn, A. EatonMaochang, LiuYuMing, ChangWeiping, Zou
we analyzed the proportion of MHCIIhineutrophils in the lung tissue of MMTV-PyMT mice after chronic pulmonary PAO1 infection using flow cytometry. As expected, the results were consistent with those in 4T1 tumor-bearing mice (Supplementary Fig.5a–c). Further...
Clinically Relevant Allergen Mixture Induces Robust Immune Response By Increasing CD11c+CD11b+MHCIIhiCD103int Lung Dendritic CellsClinically Relevant Allergen Mixture Induces Robust Immune Response By Increasing CD11c+CD11b+MHCIIhiCD103int Lung Dendritic CellsFemale Balb/c mice were sensitized intranasally...
FACS analysis suggested that decreased Ly6c lo MHCII hi AMs might make the major contribution to attenuated fibrogenesis in RBP‐J cKO mice, probably by reduced inflammatory factor release and enhanced matrix metalloproteinases expression. Using clodronate‐mediated macrophage depletion in RBP‐J ckO ...
“Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils”的研究论文,该研究首次证实慢性肺部细菌感染能促进乳腺癌的肺转移进程,并鉴定到一群名为MHCIIhi的中性粒细胞亚群在促进乳腺癌转移的过程中发挥着重要作用,结果表明,MHCIIhi中性粒细胞...
“Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils”的研究论文,该研究首次证实慢性肺部细菌感染能促进乳腺癌的肺转移进程,并鉴定到一群名为MHCIIhi的中性粒细胞亚群在促进乳腺癌转移的过程中发挥着重要作用,结果表明,MHCIIhi中性粒细胞...
“Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils”的研究论文,该研究首次证实慢性肺部细菌感染能促进乳腺癌的肺转移进程,并鉴定到一群名为MHCIIhi的中性粒细胞亚群在促进乳腺癌转移的过程中发挥着重要作用,结果表明,MHCIIhi中性粒细胞...
“Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils”的研究论文,该研究首次证实慢性肺部细菌感染能促进乳腺癌的肺转移进程,并鉴定到一群名为MHCIIhi的中性粒细胞亚群在促进乳腺癌转移的过程中发挥着重要作用,结果表明,MHCIIhi中性粒细胞...
“Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils”的研究论文,该研究首次证实慢性肺部细菌感染能促进乳腺癌的肺转移进程,并鉴定到一群名为MHCIIhi的中性粒细胞亚群在促进乳腺癌转移的过程中发挥着重要作用,结果表明,MHCIIhi中性粒细胞...