MHC I-BINDING SSX-241-49 VARIANTSSome embodiments relate to analogs of peptides corresponding to class I MHC-\nrestricted T cell epitopes and methods for their generation. These analogs can\ncontain amino acid substitutions at residues that directly interact with MHC\nmolecules, and can confer ...
15,16. Some key residues of MHC-I molecules determine the binding motifs that can be clustered into several groups14; the types of key residues within allele clusters and motif clusters are consistent to some extent15. In addition, the similarity between binding motifs can be used ...
MHCflurry also includes two expermental predictors, an "antigen processing" predictor that attempts to model MHC allele-independent effects such as proteosomal cleavage and a "presentation" predictor that integrates processing predictions with binding affinity predictions to give a composite "presentation ...
Competition-based cellular peptide binding assay for HLA class I 10.1002/0471142735.im1812s61 Google Scholar Kim et al., 2014 Y. Kim, J. Sidney, S. Buus, A. Sette, M. Nielsen, B. Peters Dataset size and composition impact the reliability of performance benchmarks for peptide-MHC binding ...
该文解析了爬行动物绿安蜥(Anolis carolinensis,俗称变色龙) MHC-I-九肽复合体(pMHC-I)的精细结构,揭示了变色龙经典MHC-I类分子独特的3D结构及其呈递抗原多肽的免疫学基础。 On the cover: The peptide binding groove of the ...
Reche PA, Glutting JP, Reinherz EL (2002) Prediction of MHC class I binding peptides using profile motifs. Hum Immunol 63:701-709Reche PA, Glutting JP, Reinherz EL. Prediction of MHC class I binding peptides using profile motifs. Hum Immunol. 2002;63: 701-709....
NetMHCpan-4.0: improved peptide-MHC class I interaction predictions integrating eluted ligand and peptide binding affinity data. J. Immunol. 199, 3360–3368 (2017). Article CAS PubMed Google Scholar Quinlan, A. R. & Hall, I. M. BEDTools: a flexible suite of utilities for comparing ...
(2004) MHC class I epitope binding prediction trained on small data sets. In, Proceedings for the third ICARIS meeting September 2004. Springer-Verlag, New York.Lundegaard,C. et al. (2004) MHC class I epitope binding prediction trained on small data sets. In Artificial Immune Systems, ...
This the corresponding repository of paperDeepSeqPan, a novel deep convolutional neural network model for pan-specific class I HLA-peptide binding affinity prediction. To cite @article{liu2019deepseqpan, title={DeepSeqPan, a novel deep convolutional neural network model for pan-specific class I HL...
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