Prediction of MHC- binding peptides of flexible lengths from sequence-derived structural and physicochemical attributes. Mol Immunol 2007;44:866-77.Cui J,,Han LY,Lin HH et al.Prediction of MHC-binding peptides of flexible lengths from sequence-derived structural and physicochemical properties. ...
Structure of a pMHC complex. (A) Front view of the crystal structure 1I4F depicting acartoonrepresentation of the MHC (HLA-A*02:01), and asticksrepresentation of the bound peptide (derived from MAGEA4, in pink). The heavy chain of the MHC receptor (alpha), which contains the binding c...
CAS号: 英文名: MHC binding peptide 英文别名: MHC binding peptide 中文名: 中文别名: CBNumber: CB11398385 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 0 MHC binding peptide化学性质安全信息 MHC binding peptide性质、用途与生产工艺 MHC binding peptide 上下游...
Schueler-Furman O,Altuvia Y,Margalit H.Examination of possible structural constraints of MHC-binding peptides by assessment of their native structure within their source proteins. Proteins . 2001Schueler-Furman O, Altubia Y, Margalit H. Examination of pos- sible structural constraints of MHC-...
The selection of peptides presented by MHC molecules is crucial for antigen discovery. Previously, several predictors have shown impressive performance on binding affinity. However, the decisive MHC residues and their relation to the selection of binding
USMPepis a simple recurrent neural network for MHC binding affinity prediction. It is competitive with state-of-the-art tools for a single model trained from scratch, while ensembling multiple regressors and language model pretraining can slightly improve its performance. In our paper we report ...
SEA as part of a fusion protein showed a >10-fold reduction in MHC class II binding compared to native SEA, and accordingly, the affinity of the F... M Dohlsten,L Abrahmsen,P Bjork,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: ...
With PUFFIN's uncertainty metrics, we define binding likelihood, the probability a peptide binds to a given MHC allele at a specified affinity threshold. Compared to affinity point estimates, we find that binding likelihood correlates better with the observed affinity and reduces false positives in ...
MHCflurry implements class I peptide/MHC binding affinity prediction. The current version provides pan-MHC I predictors supporting any MHC allele of known sequence. MHCflurry runs on Python 3.9+ using thetensorflowneural network library. It exposescommand-lineandPython libraryinterfaces. ...
MOTIVATION: Various computational methods have been proposed to tackle the problem of predicting the peptide binding ability for a specific MHC molecule. These methods are based on known binding peptide sequences. However, current available peptide databases do not have very abundant amounts of example...