two or more designed repeat domain(s), preferably designed ankyrin repeat domain(s), with binding specificity for a pMHC complex, and to such binding proteins which further comprise a binding agent having binding specificity for a protein expressed on the surface of an immune cell, preferably a...
组织相容性(histocompatibility):是指器官或组织移植时供者与受者相互接受的程度,决定了移植手术的成败与否。 MHC(major histocompatibility complex):主要组织相容性复合体,MHC是免疫细胞识别自我和非我的关键组成分子,不仅可以决定免疫应答的类型,也是决定免疫应答结局的关键。 MHC基因编码MHC...
MHC-PEPTIDE COMPLEX BINDING LIGANDS 专利名称：MHC-PEPTIDE COMPLEX BINDING LIGANDS 发明人：HOOGENBOOM, HENRICUS, RENERUS,JACOBUS, MATTHEUS,REITER, YORAM 申请号：EP03742843 申请日：20030220 公开号：EP1485075A4 公开日：20060426 专利内容由知识产权出版社提供 摘要：Disclosed are protein ligands comprising an...
Structure of a pMHC complex. (A) Front view of the crystal structure 1I4F depicting acartoonrepresentation of the MHC (HLA-A*02:01), and asticksrepresentation of the bound peptide (derived from MAGEA4, in pink). The heavy chain of the MHC receptor (alpha), which contains the binding c...
兔主要组织相容性复合体Ⅰ类(MHCⅠ/RLAⅠ)ELISA试剂盒 Rabbit major histocompatibility complexⅠ,MHCⅠ/RLAⅠ ELISA kit 人前列腺素F2α(PGF2α)ELISA试剂盒 Human Prostaglandin F2α,PGF2α ELISA kit 公司简介 上海沪峥生物科技有限公司是一家集研发,生产,销售为一体的高新技术企业,自公司成立以来,每年的销售额...
3、binding protein, CREB, 与X2盒结合)等几乎表达于所有细胞。MHCII基因反式作用子(class II transactivator, CIITA)在研究裸淋巴细胞综合征时被分离, 发现其通过影响MHCII的转录水平, 从而调节机体的免疫功能。现就CIITA调控MHCII基因转录的分子机制及可能的临床应用综述如下。1 CIITA的结构 人类CIITA基因位于16号...
The purity of Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Complex Protein (Cat. No.HL1-H82E6) is more than 90% and the molecular weight of this protein is around 45-65 kDa verified by SEC-MALS. 文尾扫码联系好友申请Protocol ...
Major histocompatibility complex (MHC)-binding peptides are essential for antigen recognition by T-cell receptors and are being explored for vaccine design. Computational methods have been developed for predicting MHC-binding peptides of fixed lengths, based on the training of relatively few non-binder...
binding cleft, a highly polymorphic region, contributing to the diversity of MHC-I-binding motifs9. There are >13,000 MHC-I alleles on a four-digit level (e.g., A*02:01) recorded in the IPD-IMGT/HLA database10, representing a particular protein sequence. Thus, it is difficult to ...
70热休克蛋白70tapasinTAP—associatedglycoproteinTAP相关糖蛋白CNXcalnexin钙联蛋白Crtcalreticulin钙网蛋白FormalinFixedandparaffinFFPET甲醛固定石蜡包埋组织embeddedtissuesErp57EndoplasmicReticlumprotein57内质网57蛋白ABCATP——bindingcassettesuperfamily转运蛋白超家族PLCPeptide——loadingcomplex肽段转运复合体链霉菌抗生物素...