ProImmune’s MHC-peptide binding assay for class II alleles is a powerful cell-freein vitroassay that can rapidly predict CD4+ T cell epitopes in any protein sequence. The assay identifies the most likely immunogenic peptides in a protein sequence, and thus can play a key role in the devel...
Contrary to the situation in activated platelets, both GPIIb and GPIIIa were equally labelled by the four peptides and the cross-linking sites were localized by protein chemical analyses of the fluorescently labelled tryptic peptides of both subunits. Thus, the localization of the cross-linking ...
MHC Class II (H2-Aa) Polyclonal Antibody 说明书 实验方案 问题与答案 技术支持 货号PA5-116820 Price (CNY) 5,258.00 100 µL 下单后预计有货时间 13-May-2025 查看价格 批量或定制请求 Application Created with Sketch. 图:1/1 MHC Class II (H2-Aa) Antibody (PA5-116820) in WB...
MHC class II is unclear. Other tumors secrete inhibitory cytokines like IL-10 to suppress MHC class II and other responses, which is particularly clear for melanomas (Dummeret al., 1996) and EBV-induced B cell tumors (Benjaminet al., 1992). TheEBVgenome encodes a homologous protein for ...
Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15...
class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lympho...
Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+...
Reith, W. et al. Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X.Cell53, 897–906 (1988). CASPubMedGoogle Scholar Moreno, C. S., Beresford, G. W., Louis-Plence, P., Morris, A. C. & Boss...
3、tor X, RFX, 与X1盒结合)、 核因子Y(nuclear factor Y, NFY, 与Y盒结合)、 cAMP反应性结合蛋白(cAMP responsive binding protein, CREB, 与X2盒结合)等几乎表达于所有细胞。MHCII基因反式作用子(class II transactivator, CIITA)在研究裸淋巴细胞综合征时被分离, 发现其通过影响MHCII的转录水平, 从而调...
3、binding protein, CREB, 与X2盒结合)等几乎表达于所有细胞。MHCII基因反式作用子(class II transactivator, CIITA)在研究裸淋巴细胞综合征时被分离, 发现其通过影响MHCII的转录水平, 从而调节机体的免疫功能。现就CIITA调控MHCII基因转录的分子机制及可能的临床应用综述如下。1 CIITA的结构 人类CIITA基因位于16号...