Consequently, no dose adjustment is required in cephalexin-treated patients pretreated with metoclopramide.doi:10.1111/j.1365-2885.2007.00831.xA P PradosV KreilG AlbarellosS WaxmanM RebueltoJohn Wiley & Sons, Ltd.Journal of Veterinary Pharmacology & Therapeutics...
This medication is only short-lasting, meaning it can and should be given multiple times throughout the day. If you miss a dose you should give it to your dog as soon as possible – unless it is almost time for the next dose, in which case skip the missed dose entirely. Your vet wi...
is sensitive to light, so the intravenous solution should be covered to prevent loss of efficacy. In people undergoing chemotherapy, metoclopramide's effectiveness may be enhanced by concurrent administration of low-dosedexamethasone, but this practice has not been critically evaluated in dogs or cats...
6 In the dog the metabolic fate of metoclopramide is different to man with conjugation being a minor metabolic pathway. The half-life in the dog does not appear to be dose dependent. 7 The wide differences in bioavailability of metoclopramide in man may contribute to the unpredictable occurrence...
The control of acute cisplatin-induced emesis — a comparative study of granisetron and a combination regimen of high-dose metoclopramide and dexamethasone. ... Chevallier,B - 《Br J Cancer》 被引量: 88发表: 1993年 Plasma Levels of Peptide YY Correlate with Cisplatin-induced Emesis in Dogs Abs...
Metoclopramide undergoes first-pass hepatic metabolism. It is excreted in the urine, about 85% of a dose being eliminated in 72 hours, 20% as unchanged metoclopramide and the remainder as sulfate or glucuronide conjugates, or as metabolites. About 5% of a dose is excreted in faeces via the ...
In therapeutic doses paracetamol is a safe analgesic, but in overdosage it can cause severe hepatic necrosis. Following oral administration it is rapidly absorbed from the gastrointestinal tract, its systemic bioavailability being dose-d... JAH Forrest,JA Clements,LF Prescott - 《Clinical Pharmacokine...
Metoclopramide has been extensively investigated as a chemoprophylactic agent for aspiration pneumonitis in children and in adults. Several original studies of patients given metoclopramide, in a dose of 10 or 20 mg either orally (PO) or intravenously (IV), demonstrated the drug's utility in reduci...
DOSE/DURATION : 143 ug/kg TOXIC EFFECTS : Cardiac - arrhythmias (including changes in conduction) REFERENCE : ICMED9 Intensive Care Medicine. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.3- 1977- Volume(issue)/page/year: 12,378,1986 TYPE OF TES...
Effect of Gongronema latifolium on gastric emptying in healthy dogs. latifolium in capsules at 100 mg/kg, 250 mg/kg and 500 mg/kg, respectively, while the prokinetic group ingested 0.5 mg/kg capsules of metoclopramide... O Sylvester,Ogbu,K Kenneth,... - 《World Journal of Gastroenterolog...