However, there is little data on survival outcomes and prognostic factors affecting survival in patients with metastatic breast cancer (MBC) in Africa. The study objective was to establish the survival of patients with MBC at a single tertiary health facility, the clinical an...
Nature Cancer volume 4, pages 128–147 (2023)Cite this article 30k Accesses 106 Altmetric Metrics details Abstract The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary ...
Scientific Reports volume 13, Article number: 3845 (2023) Cite this article 942 Accesses 1 Citations 3 Altmetric Metrics details Abstract Primary tumor resection for metastatic breast cancer (MBC) has demonstrated a survival advantage, however, not all patients with MBC benefit from surgery. The ...
SEER*Explorer: an interactive website for SEER cancer statistics. Surveillance Research Program, National Cancer Institute; 2023 Apr 19 [updated: 2023 Nov 16].https://seer.cancer.gov/statistics-network/explorer/. Accessed 16 April 2024. Kohler BA, Sherman RL, Howlader N, Jemal A, Ryerson AB,...
et al. A practical prognostic peripheral blood-based risk model for the evaluation of the likelihood of a response and survival of metastatic cancer patients treated with immune checkpoint inhibitors. BMC Cancer 23, 1186 (2023). https://doi.org/10.1186/s12885-023-11699-0 Download citation ...
The therapeutic landscape for HER2-positive metastatic breast cancer has exploded in the last two decades following the initial advent of trastuzumab, a mo
Here, we aimed to look at targeting Rac1 activity in a metastatic breast cancer setting during primary growth, local invasion, dissemination in the vasculature, and subsequent colonization of metastatic sites. Using 3D organotypic modeling of tumor-ECM interactions, fluid-flow-induced shear stress ...
HER2+ breast cancer patients are presented with either synchronous (S-BM), latent (Lat), or metachronous (M-BM) brain metastases. However, the basis for disparate metastatic fitness among disseminated tumor cells of similar oncotype within a distal organ remains unknown. Here, employing brain meta...
Despite being the hallmark of cancer that is responsible for the highest number of deaths, very little is known about the biology of metastasis. Metastatic disease typically manifests after a protracted period of undetectable disease following surgery or
et al. Toripalimab plus nab-paclitaxel in metastatic or recurrent triple-negative breast cancer: a randomized phase 3 trial. Nat Med 30, 249–256 (2024). https://doi.org/10.1038/s41591-023-02677-x Download citation Received09 June 2023 Accepted01 November 2023 Published08 January 2024 Issue...