Conclusions: UHTMB MBC is a rare, yet clinically important subset of clinically advanced breast cancer driven by APOBEC mutagenesis, with high incidence of ER+ lobular histology and frequent alterations in CDH1 and PIK3CA. In addition to potential benefit from ICI based treatment, UHTMB MBC ...
EP: 3.The Impact of Biomarkers in Clinical Decision-Making and Emergent Agents in HR+/HER2- Metastatic Breast Cancer EP: 4.Review of EMERALD Subgroup Analysis Data From SABCS 2023 EP: 5.Selecting a Second-Line Therapy for a Patient With HR+/HER2- mBC After ...
released in January 2023, recommendKISQALI as the only Category 1 preferred CDK4/6 inhibitor for first-line treatment of patients with HR+/HER2- metastatic breast cancerwhen combined
Hamilton EP, Dosunmu O, Shastry M, et al. A phase 2 study of HER3-DXd in patients (pts) with metastatic breast cancer (MBC).J Clin Oncol. 2023;41(suppl_16):1004. doi:10.1200/JCO.2023.41.16_suppl.1004
BriaCell Therapeutics Corp. is thrilled to announce continued outstanding topline survival and clinical benefit data in advanced metastatic breast cancer patients treated Bria-IMT™ in combination with an immune check point inhibitor (CPI).
Nature Reviews Cancer(2024) Breast cancer: emerging principles of metastasis, adjuvant and neoadjuvant treatment from cancer registry data Jutta Engel Renate Eckel Dieter Hölzel Journal of Cancer Research and Clinical Oncology(2023) Model-based inference of metastatic seeding rates in de novo metastatic...
The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary cancers and 102 metastases) by RNA sequencing, tumor/germline DNA ex
The B2-Score is an individual, quantitative assessment of the likelihood of overall survival for advanced breast cancer patients based on routine parameters easily accessible in daily clinical care. Although major progress has been made, the optimal therapeutic management of the individual patient is st...
"Breast Cancer Conversations" EPS 208. Unveiling the Realities of Metastatic Breast Cancer in October (Podcast Episode 2023) - Movies, TV, Celebs, and more...
Emerging studies have identified chronic psychological stress as an independent risk factor influencing breast cancer growth and metastasis. However, the effects of chronic psychological stress on pre-metastatic niche (PMN) formation and the underlying i