Thus,appears to act as an autoinducer of the mesenchyme to epithelial transition that underlies nephron development.Kevin StarkSeppo VainioGalya VassilevaAndrew P. McMahonNatureStark K, Vainio S, Vassileva G, McMahon AP (1994) Epithelial transformation of metanephric mesenchyme in the developing kidney...
Islets were previously thought to originate solely from embryonic pancreatic epithelium, but we have demonstrated that islets can originate from mesenchyme, that is, islet mesenchyme-to-epithelial transition. The aim of this study was to establish the competence of foregut mesenchyme during mesenchymal ...
During embryonic development, the kidney epithelium originates from cells that undergo a mesenchymal to epithelial transition (MET). The reverse process, e... A Boutet,CA De Frutos,PH Maxwell,... - 《Embo Journal》 被引量: 302发表: 2014年 IGF-II induces rapid β-catenin relocation to the...
Australia Epithelium-Mesenchyme Transition during Neural Crest Development Key Words Epithelial-mesenchymal transition Neural crest Cell migration TGE-ß family Integrins Abstract The neural crest is the organ system whose presence defines vertebrates. The onset of migration of neural crest cells is an ...
Epithelial–mesenchymal transition (EMT) is a vital process that takes place during embryogenesis and cancer progression. Epithelial cells shed their adhesive characteristics to acquire mesenchymal properties that allow them to become motile. Tumor cells undergoing EMT are conferred aggressive traits, such ...
such as those regulating epithelial-to-mesenchymal transition, also drive disease progression in adult life. Here, we summarize observations from different animal models and organ systems that collectively point toward a central role of epithelial-to-mesenchymal transition in driving tissue fibrosis, acute...
(Chen and Streit, 2013; Anwar et al., 2017). Indeed, forced mesenchymal-to-epithelial transition (MET) appears to mediate hair cell development, as highlighted by increased formation of cells that show swift permeability to FM1-43, a staining reagent that has been used to identify the time...
such as those regulating epithelial-to-mesenchymal transition, also drive disease progression in adult life. Here, we summarize observations from different animal models and organ systems that collectively point toward a central role of epithelial-to-mesenchymal transition in driving tissue fibrosis, acute...
The versatility of microvascular pericytes: from mesenchyme to smooth muscle? Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells ...
Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase. Tissue transglutaminase (TG2), an enzyme that catalyzes Ca(2+)-dependent aggregation and polymerization of proteins, is overexpressed in ovarian cancer cel... M Shao,L Cao,C Shen,... - 《Cancer ...