Definition Phenotypic alterations in which epithelial cells adopt characteristics of mesenchymal cells. Epithelial-to-mesenchymal transition ( EMT ) is a physiological process during normal development and a pathological process during cancer progression and fibrosis. Characteristics Epithelial cells line the ...
上皮细胞间质转型(epithelial-mesenchymal transitions, EMT)是一种生物学过程,其中具有极性的上皮细胞转变为具有运动能力的间质细胞,同时获得侵袭和迁移的能力。这一过程对于人体的多个生理和病理状态至关重要。EMT的发生涉及到复杂的信号转导途径和多种分子机制。这些机制与钙连接素、生长因子、转录因子...
Objective To investigate the effect of interleukin-10(IL-10) on epithelial to mesenchymal transition in human renal tubular cells and relevant mechanisms.───目的探讨白细胞介素10对肾小管上皮细胞转分化的影响,并初步讨论其作用机制。 Conclusions: pancreatic cancer cells resistance to chemoradiotherapy can...
总的来说,Epithelial-Mesenchymal Transition 是一个重要的生物学过程,在胚胎发育、伤口愈合和疾病进展中起到关键作用。它涉及复杂的信号通路和转录因子调控网络,对细胞特性的改变具有深远影响。对EMT的深入研究有助于理解相关疾病的发生发展机制,并可能为疾病治疗提供新的策略。
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and
例句Mesenchymal stem cells can differentiate into bone, cartilage or fat cells. 间充质干细胞能够分化成为骨、软骨或脂肪细胞。 Transition英 /træn'zɪʃ(ə)n; trɑːn-; -'sɪʃ-/美 /træn'zɪʃən/ 释义n. 过渡;转变;[分子生物] 转换;变调 ...
魏炽炬Epithelial–MesenchymalTransitionOriginofEpitheliumandMesenchyme•Therearetwomajortypesofcellarrangementsintheembryo:•epithelialcell..
The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as epithelial–mesenchymal transition (EMT), is integral in development, wound healing and stem cell behaviour, and contributes pathologically to fibrosis and cancer progression. This switch in cell differentiation ...
Epithelial Mesenchymal Transition:上皮间质转化上皮,间质,转化,上皮间,间质转化,间质转变,上皮转化 文档格式: .pdf 文档大小: 792.84K 文档页数: 15页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: 论文--毕业论文 文档标签:
Definition Phenotypic alterations in which epithelial cells adopt characteristics of mesenchymal cells. Epithelial-to-mesenchymal transition ( EMT ) is a physiological process during normal development and a pathological process during cancer progression and fibrosis. Characteristics Epithelial cells line the ex...